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Table 1 Relationship between HSD11B1 gene expression in abdominal adipose tissue and the metabolic syndrome: studies and subjects’ characteristics

From: Association of HSD11B1 polymorphic variants and adipose tissue gene expression with metabolic syndrome, obesity and type 2 diabetes mellitus: a systematic review

Author, year

Subjects’ characteristics

T2DM

Obesity

BMI (kg/m 2 )

MetS

Expression in VAT (AU)

Expression in SAT (AU)

Alberti, 2007 [6]

n: 62

12 (19.4)

62 (100.0)

37.4 ± 5.1

25 (40.3)

MetS+: 2.6 ± 0.5

MetS+: 2.0 ± 1.5

Female: 52 (83.9)

Age: 44.4 ± 11.1

MetS-: 1.7 ± 1.0

MetS-: 0.7 ± 0.4a

Ethnicity: N/D

Muñoz, 2009 [8]

n: 32

6 (18.8)

32 (100.0)

36.7 ± 3.8

16 (50.0)

MetS+: 7.5

MetS+: 11.6

Female: 21 (65.6)

MetS-: 10.3

MetS-: 12.3

Age: 40.2 ± 12.3

  

Ethnicity: N/D

  

Michalaki, 2012 [7]

n = 27

2 (7.4)

19 (70.4)

46.1 ± 6.6

11 (40.7)

Lean controls: 27.8 ± 16.0

MetS+: 86.5 ± 29.8

MetS+: 62.9 ± 24.4

 

MetS-: 107.2 ± 77.7b

MetS-: 155.9 ± 124.9

 

Female: 27 (100)

      
 

Age: 37.3 ± 9.7

      
 

Ethnicity: N/D

      
  1. Data expressed as absolute and relative frequencies or mean ± standard deviation as appropriate. T2DM: type 2 diabetes mellitus; BMI: body mass index; MetS: metabolic syndrome; VAT: visceral adipose tissue; SAT: subcutaneous adipose tissue; AU: arbitrary units; N/D: not described. aP < 0.01 vs. MetS+ group. bP < 0.01 vs. lean controls.
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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