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Table 1 Clinical and metabolic parameters of the diabetic patients with or without neuropathy and healthy control groups

From: Is calprotectin a novel biomarker of neuroinflammation in diabetic periferal neuropathy?

  DNP(+) DNP(−) HC P DNP(+)-DNP(−) p DNP(+)-HC P DNP(−)-HC
Age (years)* 52.59 (±13.56) 49.83 (±12.65) 47.15 (±7.21) 0.424 0.262 0.125
Gender (M/F) 11/18 15/15 13/14 0.435 0.590 0.550
BMI (kg/m2) 34.80 (±11.90) 40.61 (±3.70) 26.64 (±2.26) <0.001 0.001 0.001
SBP (mmHg) 130.00 (±20.00) 135.00 (±10.00) 120 (±15.00) 0.042 0.054 <0.001
DBP (mmHg) 80 (±20.47) 80 (±13.00) 75.00 (±10.00) 0.174 0.026 <0.001
FPG (mg/dl) 205 (±97.00) 117 (±32.00) 87 (±13.00) <0.001 0.001 0.001
HbA1c (%) 10.10 (±3.50) 7.15 (±1.10) 5.10 (±0.50) <0.001 0.001 0.001
Total-C (mg/dl) 180.50 (±71.00) 222.00 (±38.00) 109 (±28.00) 0.001 0.528 <0.001
HDL-C (mg/dl) 38.50 (±17.00) 48.50 (±8.00) 50.00 (±9.00) 0.003 0.002 0.183
LDL-C (mg/dl)* 115.61 (±40.09) 141.77 (±27.91) 105.26 (±25.30) 0.004 0.441 <0.001
TG (mg/dl) 214.00 (±95.00) 173.50 (±67.00) 136.00 (±39.00) 0.041 <0.001 0.001
Creatinine (mg/dl) 0.85 (±0.29) 0.86 (±0.16) 0.89 (±0.11) 0.167 0.102 0.163
Duration of DM (years) 6 (±2.00) 3 (±1.00)   0.001   
Calprotectin (ng/dl)* 8.30 (±1.48) 7.41 (±1.26) 6.18 (±1.58) 0.021 <0.001 0.017
hsCRP (mg/dl) 52.59 (±13.56) 2.40 (±2.34) 1.12 (±0.41) <0.001 <0.001 0.001
Medical Treatment 11/18    0.141   
OAD (n, %) 34.80 (±11.90) 14 (46.7%)     
Insulin (n, %) 130.00 (±20.00) 5 (16.7%)     
OAD + Insulin (n, %) 80 (±20.47) 11 (36.7%)     
  1. Body Mass Index, BMI; Fasting Blood Glucose; High density lipoprotein cholesterol, HDL-C; High sensitive C reactive protein, hsCRP; Low density lipoprotein cholesterol, LDL-C; Triglyceride, TG.