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Table 5 Relationship of IL6 -174G > C with anthropometric, metabolic and inflammatory variables

From: ADIPOQ and IL6 variants are associated with a pro-inflammatory status in obeses with cardiometabolic dysfunction

Variable Genotypes   
  GG (112) GC + CC (137) P-value
Body mass index, kg/m2 31.2 ± 6.1 30.7 ± 6.3 0.528
Waist circumference, cm 96.4 ± 16.1 92.6 ± 15.7 0.067
Waist- hip ratio 0.87 ± 0.10 0.85 ± 0.10 0.164
Body fat, % 35.5 ± 6.0 36.4 ± 6.2 0.246
BMR, kcal 1644 ± 373 1543 ± 298 0.057
Leptin, ng/mL 21.8 ± 18.6 18.6 ± 15.6 0.394
sLEPR, ng/mL 22.4 ± 23.3 19.2 ± 18.8 0.615
Adiponectin, μg/mL 24.0 ± 24.0 24.5 ± 25.9 0.755
Glucose, mg/dL 103 ± 31 102 ± 21 0.072
HbA1c, % 6.0 ± 1.4 5.9 ± 1.1 0.876
Insulin, mU/L 17.7 ± 13.6 14.3 ± 9.8 0.237
HOMA-β 57.0 ± 40.3 47.4 ± 34.4 0.148
HOMA-IR 4.9 ± 5.3 3.7 ± 2.7 0.379
Total cholesterol, mg/dL 205 ± 42 204 ± 36 0.755
HDL ccholesterol, mg/dL 56 ± 19 54 ± 12 0.823
LDL cholesterol, mg/dL 122 ± 34 127 ± 31 0.241
VLDL cholesterol, mg/dL 26 ± 19 25 ± 13 0.759
Triglycerides, mg/dL 132 ± 94 124 ± 64 0.759
Apolipoprotein AI, mg/dL 152 ± 35 148 ± 34 0.753
Apolipoprotein B, mg/dL 101 ± 27 100 ± 34 0.462
Fibrinogen, mg/dL 355 (317–407) 365 (319–420) 0.325
PAI-1, pg/mL 82.7 (57.5-133.5) 75.2 (56.3-145.9) 0.991
IL-6, pg/mL 0.48 (0.08-0.64) 0.28 (0.08-0.96) 0.288
IL-1β, pg/dL 15.0 (4.0-45.0) 13.5 (4.0-32.0) 0.033
hsCRP, mg/L 0.57 (0.13-3.2) 0.52 (0.10-2.94) 0.808
TNFα, pg/mL 2.62 (0.41-4.92) 2.29 (0.49-5.18) 0.666
  1. Number of individuals is in parenthesis. Results are shown as mean ± SD or median (interquartile range) and compared by Mann–Whitney Rank sum test. BMR: basal metabolic rate; CAD: coronary artery disease; HDL: high-density lipoprotein; LDL: low-density lipoprotein; hsCRP: high sensitive C reactive protein; IL-6: interleukin 6; IL-1β: interleukin 1beta; PAI-1: plasminogen activator inhibitor-1; sLEPR: soluble leptin receptor; TNFα: tumor necrosis factor alpha; VLDL: very low-density lipoprotein.
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