|
Variable
|
Genotypes
| | |
|---|
| |
GG (112)
|
GC + CC (137)
|
P-value
|
|---|
|
Body mass index, kg/m2
|
31.2 ± 6.1
|
30.7 ± 6.3
|
0.528
|
|
Waist circumference, cm
|
96.4 ± 16.1
|
92.6 ± 15.7
|
0.067
|
|
Waist- hip ratio
|
0.87 ± 0.10
|
0.85 ± 0.10
|
0.164
|
|
Body fat, %
|
35.5 ± 6.0
|
36.4 ± 6.2
|
0.246
|
|
BMR, kcal
|
1644 ± 373
|
1543 ± 298
|
0.057
|
|
Leptin, ng/mL
|
21.8 ± 18.6
|
18.6 ± 15.6
|
0.394
|
|
sLEPR, ng/mL
|
22.4 ± 23.3
|
19.2 ± 18.8
|
0.615
|
|
Adiponectin, μg/mL
|
24.0 ± 24.0
|
24.5 ± 25.9
|
0.755
|
|
Glucose, mg/dL
|
103 ± 31
|
102 ± 21
|
0.072
|
|
HbA1c, %
|
6.0 ± 1.4
|
5.9 ± 1.1
|
0.876
|
|
Insulin, mU/L
|
17.7 ± 13.6
|
14.3 ± 9.8
|
0.237
|
|
HOMA-β
|
57.0 ± 40.3
|
47.4 ± 34.4
|
0.148
|
|
HOMA-IR
|
4.9 ± 5.3
|
3.7 ± 2.7
|
0.379
|
|
Total cholesterol, mg/dL
|
205 ± 42
|
204 ± 36
|
0.755
|
|
HDL ccholesterol, mg/dL
|
56 ± 19
|
54 ± 12
|
0.823
|
|
LDL cholesterol, mg/dL
|
122 ± 34
|
127 ± 31
|
0.241
|
|
VLDL cholesterol, mg/dL
|
26 ± 19
|
25 ± 13
|
0.759
|
|
Triglycerides, mg/dL
|
132 ± 94
|
124 ± 64
|
0.759
|
|
Apolipoprotein AI, mg/dL
|
152 ± 35
|
148 ± 34
|
0.753
|
|
Apolipoprotein B, mg/dL
|
101 ± 27
|
100 ± 34
|
0.462
|
|
Fibrinogen, mg/dL
|
355 (317–407)
|
365 (319–420)
|
0.325
|
|
PAI-1, pg/mL
|
82.7 (57.5-133.5)
|
75.2 (56.3-145.9)
|
0.991
|
|
IL-6, pg/mL
|
0.48 (0.08-0.64)
|
0.28 (0.08-0.96)
|
0.288
|
|
IL-1β, pg/dL
|
15.0 (4.0-45.0)
|
13.5 (4.0-32.0)
|
0.033
|
|
hsCRP, mg/L
|
0.57 (0.13-3.2)
|
0.52 (0.10-2.94)
|
0.808
|
|
TNFα, pg/mL
|
2.62 (0.41-4.92)
|
2.29 (0.49-5.18)
|
0.666
|
- Number of individuals is in parenthesis. Results are shown as mean ± SD or median (interquartile range) and compared by Mann–Whitney Rank sum test. BMR: basal metabolic rate; CAD: coronary artery disease; HDL: high-density lipoprotein; LDL: low-density lipoprotein; hsCRP: high sensitive C reactive protein; IL-6: interleukin 6; IL-1β: interleukin 1beta; PAI-1: plasminogen activator inhibitor-1; sLEPR: soluble leptin receptor; TNFα: tumor necrosis factor alpha; VLDL: very low-density lipoprotein.
