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Table 4 Relationship of ADIPOQ 45 T > G with anthropometric, metabolic and inflammatory variables

From: ADIPOQ and IL6 variants are associated with a pro-inflammatory status in obeses with cardiometabolic dysfunction

Variable

Genotypes

  
 

TT (163)

TG + GG (86)

P-value

Body mass index, kg/m2

30.9 ± 6.2

31.1 ± 6.2b

0.818

Waist circumference, cm

94.4 ± 16.4

94.1 ± 15.3

0.881

Waist- hip ratio

0.86 ± 0.10

0.87 ± 0.10

0.249

Body fat, %

35.8 ± 6.0

36.3 ± 6.5

0.527

BMR, kcal

1611 ± 336

1530 ± 328

0.190

Leptin, ng/mL

20.5 ± 17.6

18.8 ± 15.8

0.666

sLEPR, ng/mL

21.0 ± 21.9

19.6 ± 18.6

0.614

Adiponectin, μg/mL

25.7 ± 25.4

21.5 ± 24.0

0.442

Glucose, mg/dL

101 ± 25

104 ± 27

0.464

HbA1c, %

5.9 ± 1.2

5.9 ± 1.3

0.476

Insulin, mU/L

15.3 ± 1.6

17.6 ± 12.7

0.181

HOMA-β

50.7 ± 38.6

56.0 ± 35.3

0.205

HOMA-IR

4.1 ± 4.0

5.0 ± 4.8

0.153

Total cholesterol, mg/dL

205 ± 36

204 ± 43

0.663

HDL ccholesterol, mg/dL

55 ± 15

53 ± 16

0.205

LDL cholesterol, mg/dL

125 ± 32

124 ± 34

0.816

VLDL cholesterol, mg/dL

25 ± 14

27 ± 19

0.475

Triglycerides, mg/dL

124 ± 70

135 ± 93

0.475

Apolipoprotein AI, mg/dL

151 ± 35

148 ± 33

0.557

Apolipoprotein B, mg/dL

100 ± 27

100 ± 38

0.469

Fibrinogen, mg/dL

361 (319–423)

353 (316–399)

0.327

PAI-1, pg/mL

74.5 (55.4-138.8)

81.9 (58.2-137.7)

0.713

IL-6, pg/mL

0.28 (0.08-0.64)

0.54 (0.28-1.4)

0.012

IL-1β, pg/dL

14 (4.0-23.0)

22 (4.6-55.7)

0.003

hsCRP, mg/L

0.54 (0.1-3.1)

0.56 (0.14-3.0)

0.980

TNFα, pg/mL

1.45 (0.34-4.81)

2.9 (1.06-5.84)

0.031

  1. Number of individuals is in parenthesis. Results are shown as mean ± SD or median (interquartile range) and compared by Mann–Whitney Rank sum test. BMR: basal metabolic rate; CAD: coronary artery disease; HDL: high-density lipoprotein; LDL: low-density lipoprotein; hsCRP: high sensitive C reactive protein; IL-6: interleukin 6; IL-1β: interleukin 1beta; PAI-1: plasminogen activator inhibitor-1; sLEPR: soluble leptin receptor; TNFα: tumor necrosis factor alpha; VLDL: very low-density lipoprotein.