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Table 4 Relationship of ADIPOQ 45 T > G with anthropometric, metabolic and inflammatory variables

From: ADIPOQ and IL6 variants are associated with a pro-inflammatory status in obeses with cardiometabolic dysfunction

Variable Genotypes   
  TT (163) TG + GG (86) P-value
Body mass index, kg/m2 30.9 ± 6.2 31.1 ± 6.2b 0.818
Waist circumference, cm 94.4 ± 16.4 94.1 ± 15.3 0.881
Waist- hip ratio 0.86 ± 0.10 0.87 ± 0.10 0.249
Body fat, % 35.8 ± 6.0 36.3 ± 6.5 0.527
BMR, kcal 1611 ± 336 1530 ± 328 0.190
Leptin, ng/mL 20.5 ± 17.6 18.8 ± 15.8 0.666
sLEPR, ng/mL 21.0 ± 21.9 19.6 ± 18.6 0.614
Adiponectin, μg/mL 25.7 ± 25.4 21.5 ± 24.0 0.442
Glucose, mg/dL 101 ± 25 104 ± 27 0.464
HbA1c, % 5.9 ± 1.2 5.9 ± 1.3 0.476
Insulin, mU/L 15.3 ± 1.6 17.6 ± 12.7 0.181
HOMA-β 50.7 ± 38.6 56.0 ± 35.3 0.205
HOMA-IR 4.1 ± 4.0 5.0 ± 4.8 0.153
Total cholesterol, mg/dL 205 ± 36 204 ± 43 0.663
HDL ccholesterol, mg/dL 55 ± 15 53 ± 16 0.205
LDL cholesterol, mg/dL 125 ± 32 124 ± 34 0.816
VLDL cholesterol, mg/dL 25 ± 14 27 ± 19 0.475
Triglycerides, mg/dL 124 ± 70 135 ± 93 0.475
Apolipoprotein AI, mg/dL 151 ± 35 148 ± 33 0.557
Apolipoprotein B, mg/dL 100 ± 27 100 ± 38 0.469
Fibrinogen, mg/dL 361 (319–423) 353 (316–399) 0.327
PAI-1, pg/mL 74.5 (55.4-138.8) 81.9 (58.2-137.7) 0.713
IL-6, pg/mL 0.28 (0.08-0.64) 0.54 (0.28-1.4) 0.012
IL-1β, pg/dL 14 (4.0-23.0) 22 (4.6-55.7) 0.003
hsCRP, mg/L 0.54 (0.1-3.1) 0.56 (0.14-3.0) 0.980
TNFα, pg/mL 1.45 (0.34-4.81) 2.9 (1.06-5.84) 0.031
  1. Number of individuals is in parenthesis. Results are shown as mean ± SD or median (interquartile range) and compared by Mann–Whitney Rank sum test. BMR: basal metabolic rate; CAD: coronary artery disease; HDL: high-density lipoprotein; LDL: low-density lipoprotein; hsCRP: high sensitive C reactive protein; IL-6: interleukin 6; IL-1β: interleukin 1beta; PAI-1: plasminogen activator inhibitor-1; sLEPR: soluble leptin receptor; TNFα: tumor necrosis factor alpha; VLDL: very low-density lipoprotein.