Table 3 Influence of clinical, biochemical and genetic variables on the risk for overweight and obesity: Univariate logistic regression analysis

Clinical and anthropometric variables

Age, years

1.02

0.97 – 1.06

0.453

1.03

0.99 – 1.07

0.145

Gender [ref: male]

0.37

0.11 – 1.25

0.110

0.25

0.08 – 0.73

0.011

Ethnics [ref: white]

0.64

0.26 – 1.55

0.318

0.67

0.31 – 1.43

0.297

Menopause

1.13

0.50 – 2.52

0.774

0.54

0.27 – 1.08

0.081

Hypertension

2.48

0.92 – 6.72

0.074

5.32

2.25 – 12.60

<0.001

T2DM

1.42

0.64 – 3.15

0.390

4.40

2.23 – 8.69

<0.001

Dyslipidemia

3.30

1.48 – 7.38

0.004

5.02

2.53 – 9.97

<0.001

Family history of CAD

Tobacco smoking

1.09

0.40 – 2.94

0.872

0.71

0.30 – 1.69

0.437

Alcohol consumption

1.96

0.17 – 22.32

0.587

1.80

0.21 -15.77

0.596

Physical exercise practice

0.93

0.43 – 2.00

0.845

0.41

0.21 – 0.79

0.008

Waist circumference, cm

1.21

1.12 – 1.30

<0.001

1.42

1.30 – 1.55

<0.001

Body fat, %

1.13

1.04 – 1.23

0.004

1.34

1.23 – 1.46

<0.001

Biochemical parameters

Leptin, ng/mL

1.02

0.98 – 1.06

0.434

1.05

1.01 – 1.08

0.006

sLEPR, ng/mL

0.99

0.90 – 1.01

0.397

0.99

0.97 – 1.01

0.421

Adiponectin, μg/mL

0.99

0.97–- 1.01

0.155

1.00

0.99 – 1.02

0.555

Fibrinogen, mg/dL

1.01

1.00 – 1.01

0.037

1.01

1.00 – 1.01

<0.001

PAI-1, pg/mL

1.03

0.98 – 1.08

0.204

1.04

1.00 – 1.08

0.057

IL-6, pg/mL

1.23

0.91 – 1.67

0.183

1.24

0.92 – 1.66

0.154

IL-1β, pg/dL

1.08

1.01 – 1.16

0.029

1.14

1.06 – 1.22

<0.001

hsCRP, mg/L

1.24

0.87 – 1.76

0.232

1.75

1.28 – 2.3

<0.001

TNFα, pg/mL

1.18

0.96 – 1.45

0.123

1.35

1.13 – 1.62

0.001

Polymorphisms

ADIPOQ 45 T > G (ref TT)

1.03

0.46 - 2.32

0.946

1.06

0.54 - 2.09

0.858

IL6 -174G > C (ref GG)

1.50

0.68 - 3.30

0.317

0.95

0.50 - 1.81

0.884