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Table 1 Characteristics of study population

From: IRS-1 gene polymorphism and DNA damage in pregnant women with diabetes or mild gestational hyperglycemia

 

Pregnant women

 

Non-diabetic

MGH

Diabetic

Number of subjects

62

63

101

Age (years)

29.70 ± 5.50

31.50 ± 4.20

31.30 ± 5.40

Glycemic Mean (mg/dL)

80.56 ± 8.76

97.69 ± 7.85*

108.50 ± 15.82* #

Initial BMI (Kg/m2)

29.34 ± 8.39

31.93 ± 9.43

32.49 ± 8.29

Final BMI (Kg/m2)

33.82 ± 8.01

36.17 ± 7.91

36.12 ± 6.62

HbA1c

5.45 ± 0.53

5.74 ± 0.67

6.33 ± 0.90* #

  

Newborns

 
 

Non-diabetic

MGH

Diabetic

Number of subjects

31

12

42

Glycemia (mg/dL)

64.76 ± 19.45

66.73 ± 22.59

69.56 ± 31.84

Weight Classification a

   

SGA

03 (10.0%)

00 (0.0%)

03 (7.3%)

AGA

27 (90.0%)

8 (66.6%)αβ

34 (82.9%)

LGA

0 (0.0%)

4 (33.3%)αβ

4 (9.7%)α

  1. MGH: Mild gestational hyperglycemia.
  2. BMI: Body Mass Index, HbA1C: Glycated Hemoglobin, SGA: small for gestational age.
  3. AGA: adequate for gestational age, LGA: large for gestational age.
  4. Data presented as mean ± standard deviation.
  5. *p < 0.05 – statistically significant compared to non-diabetic group (Tukey’s multiple comparison test).
  6. #p < 0.05 – statistically significant compared to MGH group (Tukey’s multiple comparison test).
  7. αp < 0.05 – statistically significant compared to newborns of non-diabetic group (Chi-square test).
  8. βp < 0.05 – statistically significant compared to newborns of diabetic group (Chi-square test).