Skip to main content

Advertisement

Table 3 Total AUC for IL-6, adiponectin, leptin and GLP-1 in response to meal intake

From: Effects of Roux-en-Y gastric bypass on fasting and postprandial inflammation-related parameters in obese subjects with normal glucose tolerance and in obese subjects with type 2 diabetes

Total AUC Mean (95% CI) P -value
IL-6 (pg/ml × 240 min) N= 18   0.001
Pre-RYGB 1525 (1151; 1899)  
1 week 3897 (530; 7264)  
3 months 1471 (1099; 1843)  
1 year 1312 (803; 1821)b  
Adiponectin (μg/ml × 240 min) N= 18   <0.0001
Pre-RYGB 2006 (1615; 2398)  
1 week 1891 (1505; 2278)  
3 months 2188 (1801; 2575)b  
1 year 3541 (2821; 4261)a,b,c  
Leptin (ng/ml × 240 min) N= 18   <0.0001
Pre-RYGB 16997 (11138; 22856)  
1 week 8883 (5600; 12166)a  
3 months 9113 (4981; 13245)a  
1 year 7883 (3904; 11862)a  
GLP-1 (pmol/l × 240 min) N= 21   <0.0001
Pre-RYGB 2742 (2433; 3051)  
1 week 10257 (7962; 12551)a  
3 months 11606 (8833; 14379)a  
1 year 11642 (8398; 14886)a  
  1. Total AUC for IL-6 (N = 18), adiponectin (N = 18), leptin (N = 18), and GLP-1 (N = 21) in response to meal intake measured in the whole study population before (Pre-RYGB), 1 week, 3 months, and 1 year after Roux-en-Y gastric bypass. Data are presented as mean with 95% confidence interval (CI). Comparisons between time-points was made using ANOVA (non-parametric Friedman test for repeated measures) followed by Dunn’s multiple test for statistical differences, adifferent from pre-surgical levels, bdifferent form one-week level, and cdifferent from one year level, P < 0.05.