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Table 3 Total AUC for IL-6, adiponectin, leptin and GLP-1 in response to meal intake

From: Effects of Roux-en-Y gastric bypass on fasting and postprandial inflammation-related parameters in obese subjects with normal glucose tolerance and in obese subjects with type 2 diabetes

Total AUC

Mean (95% CI)

P -value

IL-6 (pg/ml × 240 min) N  = 18

 

0.001

Pre-RYGB

1525 (1151; 1899)

 

1 week

3897 (530; 7264)

 

3 months

1471 (1099; 1843)

 

1 year

1312 (803; 1821)b

 

Adiponectin (μg/ml × 240 min) N  = 18

 

<0.0001

Pre-RYGB

2006 (1615; 2398)

 

1 week

1891 (1505; 2278)

 

3 months

2188 (1801; 2575)b

 

1 year

3541 (2821; 4261)a,b,c

 

Leptin (ng/ml × 240 min) N  = 18

 

<0.0001

Pre-RYGB

16997 (11138; 22856)

 

1 week

8883 (5600; 12166)a

 

3 months

9113 (4981; 13245)a

 

1 year

7883 (3904; 11862)a

 

GLP-1 (pmol/l × 240 min) N  = 21

 

<0.0001

Pre-RYGB

2742 (2433; 3051)

 

1 week

10257 (7962; 12551)a

 

3 months

11606 (8833; 14379)a

 

1 year

11642 (8398; 14886)a

 
  1. Total AUC for IL-6 (N = 18), adiponectin (N = 18), leptin (N = 18), and GLP-1 (N = 21) in response to meal intake measured in the whole study population before (Pre-RYGB), 1 week, 3 months, and 1 year after Roux-en-Y gastric bypass. Data are presented as mean with 95% confidence interval (CI). Comparisons between time-points was made using ANOVA (non-parametric Friedman test for repeated measures) followed by Dunn’s multiple test for statistical differences, adifferent from pre-surgical levels, bdifferent form one-week level, and cdifferent from one year level, P < 0.05.