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Table 1 Characteristics of type 2 diabetic subjects and normal glucose tolerant subjects

From: Effects of Roux-en-Y gastric bypass on fasting and postprandial inflammation-related parameters in obese subjects with normal glucose tolerance and in obese subjects with type 2 diabetes

   Pre-RYGB 1 week 3 months 1 year * P value
Weight (kg) N (T2D; NGT) 13; 12 12; 12 13; 11 13; 11  
T2D 129 ± 14 127 ± 13 112 ± 15*** 101 ± 20*** <0.0001
NGT 127 ± 15 124 ± 15 106 ± 13** 95 ± 16*** <0.0001
P value 0.57 0.29 0.25 0.49  
BMI (kg/m 2 ) N (T2D; NGT) 13; 12 12; 12 13; 11 13; 11  
T2D 43.2 ± 5.3 42.5 ± 5.5 37.2 ± 5.8*** 34.8 ± 7.9*** <0.0001
NGT 41.5 ± 4.8 40.5 ± 4.5 34.4 ± 3.4** 31.3 ± 4.8*** <0.0001
P value 0.34 0.4 0.12 0.42  
Glucose (mmol/L) N (T2D; NGT) 13; 12 12; 12 13; 11 13; 11  
T2D 8.9 ± 2.3 7.0 ± 1.1* 6.9 ± 1.6** 6.3 ± 1.6*** 0.0001
NGT 5.5 ± 0.7††† 5.0 ± 0.6††† 4.9 ± 0.4**††† 5.0 ± 0.3†† 0.01
P value <0.0001 0.0002 0.001 0.007  
HbA1c (%) N (T2D; NGT) 13; 12   13; 11 13; 10  
T2D 7.0 ± 0.9   5.9 ± 0.8 5.6 ± 0.6*** 0.0007
NGT 5.5 ± 0.4†††   5.4 ± 0.3 5.4 ± 0.3 0.22
P value 0.0002   0.06 0.24  
Insulin (mmol/L) N (T2D; NGT) 13; 12 12; 12 13; 11 13; 11  
T2D 125.0 ± 77.0 72.9 ± 32.1* 58.1 ± 35.4*** 46.7 ± 27.1*** <0.0001
NGT 82.2 ± 28.3 49.4 ± 13.5 42.8 ± 13.8** 35.8 ± 16.5*** 0.0001
P value 0.29 0.053 0.6 0.45  
HOMA-IR N (T2D; NGT) 13; 12 12; 12 13; 11 13; 11  
T2D 6.6 ± 3.6 3.2 ± 1.5* 2.5 ± 1.7** 1.8 ± 1.1*** <0.0001
NGT 2.9 ± 1.1†† 1.6 ± 0.5†† 1.3 ± 0.5* 1.1 ± 0.5*** 0.0002
P value 0.002 0.001 0.047 0.11  
  1. Characteristics of T2D subjects and NGT subjects before (Pre-RYGB), 1 week, 3 months, and 1 year after Roux-en-Y gastric bypass. Data are presented as mean ± SD. BMI, body mass index; HbA1c, glycated hemoglobin; HOMA-IR, homeostasis model assessment of insulin resistance; NGT, normal glucose tolerance; T2D, type 2 diabetes. * P-value for overall comparison of time-points within groups, *P < 0.05, **P < 0.01, ***P < 0.0001; †P-value for comparison between groups, P < 0.05, †† P < 0.01, ††† P < 0.0001.