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Table 1 Clinical characteristics of subjects among NGT, IGR, T2DM, non-MetS and MetS groups

From: Peripheral neuropathy is associated with insulin resistance independent of metabolic syndrome

 

NGT(n = 458)

IGR(n = 1043)

T2DM(n = 534)

no-MetS(n = 1065)

MetS(n = 970)

 

non-PN(n = 451)

PN(n = 7)

non-PN(n = 1014)

PN(n = 29)

non-PN(n = 489)

PN(n = 45)

non-PN(n = 1037)

PN(n = 28)

non-PN(n = 917)

PN(n = 53)

Male/All

141/451

0/7

348/1014

9/29

217/489

13/45*

391/1037

9/28

315/917

13/53

Age(year)

60.7 ± 11.0

76.7 ± 9.7*

60.7 ± 9.3

71.4 ± 9.7*

63.5 ± 9.7

69.6 ± 9.5*

60.5 ± 10.2

76.6 ± 10.6*

61.7 ± 9.5

70.5 ± 9.3*

Smoking history

68/451

0/7

134/1014

2/29

78/489

4/45

159/1037

1/28

121/917

5/53

Duration of T2DM(years)

4.2 ± 6.3

11.2 ± 9.6*

BMI (kg/m2)

23.5 ± 3.1

25.4 ± 4.3

24.3 ± 3.4

24.3 ± 3.9

25.5 ± 3.8

25.8 ± 4.3

23.1 ± 3.0

24.1 ± 4.1

25.9 ± 3.4

25.8 ± 4.1

WC(cm)

82.4 ± 9.1

90.3 ± 11.0

85.4 ± 9.6

88.0 ± 12.2

90.2 ± 10.2

92.5 ± 10.5

81.6 ± 8.9

85.9 ± 12.8

90.8 ± 9.0

93.2 ± 9.5*

SBP (mmHg)

124.1 ± 18.4

136.1 ± 19.5

126.1 ± 18.6

132.4 ± 23.6

135.2 ± 20.9

139.4 ± 23.0

121.5 ± 17.8

130.1 ± 21.6*

135.2 ± 19.1

140.0 ± 23.0

DBP (mmHg)

78.7 ± 10.5

80.6 ± 10.0

79.8 ± 10.2

77.4 ± 12.0

81.7 ± 10.7

79.7 ± 11.0

77.1 ± 9.6

74.6 ± 10.1

83.3 ± 10.4

81.3 ± 11.1

FBG (mmol/L)

4.5 ± 0.6

4.3 ± 0.3

5.4 ± 0.8

5.3 ± 0.8

7.3 ± 2.7

8.1 ± 3.8

5.2 ± 1.5

5.3 ± 1.4

6.2 ± 2.0

7.6 ± 3.6*

HbA1c (%)

5.4 ± 0.2

5.5 ± 0.1

5.8 ± 0.3

5.7 ± 0.4

7.1 ± 1.5

7.5 ± 1.6

5.8 ± 0.8

6.0 ± 0.9

6.3 ± 1.2

7.0 ± 1.7*

TG (mmol/L)

1.5 ± 0.9

1.4 ± 0.7

1.7 ± 1.0

1.4 ± 0.7

2.1 ± 1.6

1.9 ± 1.6

1.3 ± 0.6

1.0 ± 0.4*

2.2 ± 1.4

2.0 ± 1.5

TC (mmol/L)

5.2 ± 1.0

5.4 ± 0.6

5.4 ± 1.0

5.1 ± 0.9*

5.5 ± 1.2

5.5 ± 1.3

5.3 ± 1.0

5.3 ± 1.4

5.5 ± 1.1

5.3 ± 1.0

HDL-C (mmol/L)

1.4 ± 0.3

1.3 ± 0.2

1.4 ± 0.3

1.3 ± 0.4

1.3 ± 0.3

1.2 ± 0.3

1.5 ± 0.3

1.5 ± 0.3

1.2 ± 0.3

1.2 ± 0.3

LDL-C(mmol/L)

3.1 ± 0.7

3.5 ± 0.4

3.1 ± 0.7

2.9 ± 0.6

3.2 ± 0.8

3.3 ± 0.9

3.1 ± 0.7

3.2 ± 1.0

3.2 ± 0.8

3.2 ± 0.7

Treatment of diabetes

0.2%

3.4%

36.0%

71.1%*

4.0%

17.8%*

14.9%

52.8%*

Treatment of dyslipidemia

2.9%

14.3%

1.1%

0.0%

2.2%

6.7%

0.9%

3.6%

2.8%

5.7%

Treatment of hypertension

22.7%

28.6%

22.8%

44.0%*

43.6%

45.5%

16.0%

35.3%*

41.6%

49.0%

  1. Categorical variables were expressed as numbers or percentages.
  2. Continuous variables were expressed as mean ± SD.
  3. NGT: normal glucose tolerance; IGR: impaired glucose regulation; T2DM: type 2 diabetes mellitus; MetS: metabolic syndrome; PN: peripheral neuropathy; BMI: body mass index; WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1c: glycated hemoglobin A1c; FBG: fasting blood glucose; HDL-C: high density lipoprotein-cholesterol; LDL-C: low density lipoprotein-cholesterol.
  4. *significantly different from non-PN and corresponding PN groups (P value < 0.05).