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Table 1 Clinical characteristics of subjects among NGT, IGR, T2DM, non-MetS and MetS groups

From: Peripheral neuropathy is associated with insulin resistance independent of metabolic syndrome

  NGT(n = 458) IGR(n = 1043) T2DM(n = 534) no-MetS(n = 1065) MetS(n = 970)
  non-PN(n = 451) PN(n = 7) non-PN(n = 1014) PN(n = 29) non-PN(n = 489) PN(n = 45) non-PN(n = 1037) PN(n = 28) non-PN(n = 917) PN(n = 53)
Male/All 141/451 0/7 348/1014 9/29 217/489 13/45* 391/1037 9/28 315/917 13/53
Age(year) 60.7 ± 11.0 76.7 ± 9.7* 60.7 ± 9.3 71.4 ± 9.7* 63.5 ± 9.7 69.6 ± 9.5* 60.5 ± 10.2 76.6 ± 10.6* 61.7 ± 9.5 70.5 ± 9.3*
Smoking history 68/451 0/7 134/1014 2/29 78/489 4/45 159/1037 1/28 121/917 5/53
Duration of T2DM(years) 4.2 ± 6.3 11.2 ± 9.6*
BMI (kg/m2) 23.5 ± 3.1 25.4 ± 4.3 24.3 ± 3.4 24.3 ± 3.9 25.5 ± 3.8 25.8 ± 4.3 23.1 ± 3.0 24.1 ± 4.1 25.9 ± 3.4 25.8 ± 4.1
WC(cm) 82.4 ± 9.1 90.3 ± 11.0 85.4 ± 9.6 88.0 ± 12.2 90.2 ± 10.2 92.5 ± 10.5 81.6 ± 8.9 85.9 ± 12.8 90.8 ± 9.0 93.2 ± 9.5*
SBP (mmHg) 124.1 ± 18.4 136.1 ± 19.5 126.1 ± 18.6 132.4 ± 23.6 135.2 ± 20.9 139.4 ± 23.0 121.5 ± 17.8 130.1 ± 21.6* 135.2 ± 19.1 140.0 ± 23.0
DBP (mmHg) 78.7 ± 10.5 80.6 ± 10.0 79.8 ± 10.2 77.4 ± 12.0 81.7 ± 10.7 79.7 ± 11.0 77.1 ± 9.6 74.6 ± 10.1 83.3 ± 10.4 81.3 ± 11.1
FBG (mmol/L) 4.5 ± 0.6 4.3 ± 0.3 5.4 ± 0.8 5.3 ± 0.8 7.3 ± 2.7 8.1 ± 3.8 5.2 ± 1.5 5.3 ± 1.4 6.2 ± 2.0 7.6 ± 3.6*
HbA1c (%) 5.4 ± 0.2 5.5 ± 0.1 5.8 ± 0.3 5.7 ± 0.4 7.1 ± 1.5 7.5 ± 1.6 5.8 ± 0.8 6.0 ± 0.9 6.3 ± 1.2 7.0 ± 1.7*
TG (mmol/L) 1.5 ± 0.9 1.4 ± 0.7 1.7 ± 1.0 1.4 ± 0.7 2.1 ± 1.6 1.9 ± 1.6 1.3 ± 0.6 1.0 ± 0.4* 2.2 ± 1.4 2.0 ± 1.5
TC (mmol/L) 5.2 ± 1.0 5.4 ± 0.6 5.4 ± 1.0 5.1 ± 0.9* 5.5 ± 1.2 5.5 ± 1.3 5.3 ± 1.0 5.3 ± 1.4 5.5 ± 1.1 5.3 ± 1.0
HDL-C (mmol/L) 1.4 ± 0.3 1.3 ± 0.2 1.4 ± 0.3 1.3 ± 0.4 1.3 ± 0.3 1.2 ± 0.3 1.5 ± 0.3 1.5 ± 0.3 1.2 ± 0.3 1.2 ± 0.3
LDL-C(mmol/L) 3.1 ± 0.7 3.5 ± 0.4 3.1 ± 0.7 2.9 ± 0.6 3.2 ± 0.8 3.3 ± 0.9 3.1 ± 0.7 3.2 ± 1.0 3.2 ± 0.8 3.2 ± 0.7
Treatment of diabetes 0.2% 3.4% 36.0% 71.1%* 4.0% 17.8%* 14.9% 52.8%*
Treatment of dyslipidemia 2.9% 14.3% 1.1% 0.0% 2.2% 6.7% 0.9% 3.6% 2.8% 5.7%
Treatment of hypertension 22.7% 28.6% 22.8% 44.0%* 43.6% 45.5% 16.0% 35.3%* 41.6% 49.0%
  1. Categorical variables were expressed as numbers or percentages.
  2. Continuous variables were expressed as mean ± SD.
  3. NGT: normal glucose tolerance; IGR: impaired glucose regulation; T2DM: type 2 diabetes mellitus; MetS: metabolic syndrome; PN: peripheral neuropathy; BMI: body mass index; WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1c: glycated hemoglobin A1c; FBG: fasting blood glucose; HDL-C: high density lipoprotein-cholesterol; LDL-C: low density lipoprotein-cholesterol.
  4. *significantly different from non-PN and corresponding PN groups (P value < 0.05).
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