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Table 3 Average morphometric data of sural nerves myelinated fibers from the four experimental groups: normotensive Wistar rat control group (WR), normotensive Wistar rat chronically induced diabetes group (WR + STZ), spontaneously hypertensive rat group (SHR), spontaneously hypertensive rat chronically induced diabetes group (SHR + STZ)

From: Association of chronic diabetes and hypertension in sural nerve morphometry: an experimental study

 

WR

WR + STZ

SHR

SHR + STZ

Myelinated fiber area (ÎĽm2)

33.46 ± 0.74

29.00 ± 0.89*

25.65 ± 0.62*

27.47 ± 1.47*

Myelinated fiber diameter (ÎĽm)

5.48 ± 0.07

5.10 ± 0.08*

4.78 ± 0.07*

4.81 ± 0.10*

Myelin sheath area (ÎĽm2)

25.69 ± 0.55

21.56 ± 0.80*

16.49 ± 0.40*+

17.90 ± 0.75*+

Myelinated axon area (ÎĽm2)

8.19 ± 0.25

7.38 ± 0.26

9.16 ± 0.25+

9.56 ± 0.54+

Myelinated axon diameter (ÎĽm)

2.67 ± 0.05

2.65 ± 0.05

2.86 ± 0.04

2.80 ± 0.09

g ratio

0.49 ± 0.01

0.53 ± 0.01

0.61 ± 0.01*+

0.60 ± 0.01

  1. *indicates significant difference compared to Normotensive Wistar rat (WR) group; + indicates significant difference compared to Normotensive Wistar rat with chronic induced diabetes (WR + STZ) group.