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Table 2 Effect of resveratrol on serum glucose, oxidative stress markers and lipid profile in studied groups

From: Neuroprotective effect of resveratrol in diabetic cerebral ischemic-reperfused rats through regulation of inflammatory and apoptotic events

 

N

D

D + Res

DIR

DIR + Res

Serum glucose (mg/dl)

103.3 ± 8.2

341.8 ± 21.42*

241.3 ± 10.63a

348.5 ± 10.8*

261.7 ± 14.83b

Cerebral MDA (nmol/g.tissue)

178.8 ± 14.18

442.0 ± 17.05*

271.8 ± 29.4a

974.8 ± 45.19*#

684.8 ± 51.16b

Cerebral GSH (nmol/g.tissue)

320.5 ± 26.73

141.2 ± 17.79*

234.7 ± 12.42a

100.7 ± 13.8*#

226.3 ± 9.81b

Serum TAG (mg/dl)

72.5 ± 6.95

204.8 ± 14.66*

121.3 ± 10.75a

220.5 ± 12.34*

127 ± 11.25b

Serum TC (mg/dl)

77.83 ± 6.62

164.7 ± 14.58*

107.8 ± 10.17a

168.3 ± 14.42*

111.9 ± 10.54b

Serum HDL-C (mg/dl)

26.67 ± 2.07

17 ± 1.52*

22.17 ± 1.6a

16.02 ± 1.44*

20.87 ± 1.48b

Serum LDL-C (mg/dl)

36.67 ± 4.68

106.7 ± 12.29*

61.4 ± 9.78a

108.2 ± 12.81*

65.62 ± 10.06b

Atherogenic index

1.37 ± 0.21

6.33 ± 1.11*

2.77 ± 0.55a

6.83 ± 1.25*

3.18 ± 0.57b

  1. All results were expressed as mean ± SD, (n = 6).
  2. *Significantly different from N at P < 0.01.
  3. #Significantly different from D at P < 0.01.
  4. aSignificantly different from D at P < 0.05.
  5. bSignificantly different from DIR at P < 0.05.
  6. N, D, D + Res, DIR, DIR + Res represent control, diabetic, diabetic treated with resveratrol, diabetic with cerebral ischemic-reperfusion, diabetic with cerebral ischemic-reperfusion treated with resveratrol groups.