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Figure 3 | Diabetology & Metabolic Syndrome

Figure 3

From: Relationship between gut hormones and glucose homeostasis after bariatric surgery

Figure 3

General schematic representation of the mechanisms after RYGB that contribute for glycemic homeostasis and type 2 diabetes control. Legend: RYGB can control food intake through gastrointestinal hormones action. The reduced gastric pouch favors gastric emptying. In the liver, there is insulin sensitivity improvement, with decrease of insulin resistance and glucose output. In adipose tissue occurs decrease of inflammation and production oh proinflammatory cytokines, improving insulin sensitivity. In the pancreas the release of insulin increase and all these change leads to T2D remission. Abbreviations: GLP-1: Glucagon Like Peptide-1; PYY: Peptide YY; OXM: Oxyntomodulin.

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