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Table 4 Relationships between multiple risk factors and cardiovascular autonomic neuropathy

From: Association between Brachial-Ankle pulse wave velocity and cardiac autonomic neuropathy in type 2 diabetes

Variable Model A Model B
Adjusted odds ratio (95% CI) P Adjusted odds ratio (95% CI) P
Age > 60 years, no vs yes 2.247(1.160-4.349) 0.016 2.837(1.365-5.897) 0.005
Gender(male) 1.513(0.776-2.951) 0.225 1.692(0.840-3.406) 0.141
Duration of diabetes(per decade) 0.848(0.474-1.517) 0.578 0.832(0.454-1.523) 0.550
BMI(per kg/m2) 0.888(0.800-0.985) 0.024 0.888(0.798-0.988) 0.029
Waist-to-hip ratio* 2.205(0.014-353.823) 0.760 2.119(0.320-14.033) 0.436
systolic blood pressure(per 10 mmHg) 1.008(0.989-1.027) 0.391 1.017(0.996-1.038) 0.108
diastolic blood pressure(per 10 mmHg) 0.997(0.966-1.028) 0.840 0.977(0.919-1.039) 0.457
Current smoker, no vs yes 1.660(0.792-3.479) 0.179 1.331(0.599-2.955) 0.482
Alcohol consumption, no vs yes 1.521(0.702-3.292) 0.287 1.474(0.660-3.293) 0.344
Hypertension, no vs yes 1.262(0.645-2.468) 0.497 1.563(0.767-3.183) 0.219
HbA1c(per 1%) 1.115(0.929-1.338) 0.244 1.091(0.905-1.314) 0.550
fasting glucose(per 1 mmol/l)* 1.020(0.922-1.128) 0.700 0.594(0.176-2.007) 0.401
Creatinine (per 1 μmol/L)* 0.954(0.230-3.950) 0.948 1.119(0.256-4.882) 0.881
eGFR( per 1 ml/min/1.73 m2) 0.999(0.987-1.011) 0.874 0.995(0.982-1.008) 0.465
total cholesterol(per 1 mmol/l) 1.046(0.807-1.355) 0.735 1.024(0.778-1.349) 0.864
Triglyceride(per 1 mmol/l)* 0.823(0.462-1.469) 0.511 0.969(0.524-1.795) 0.921
LDL cholesterol(per 1 mmol/l)* 1.405(0.426-4.634) 0.576 1.470(0.423-5.113) 0.545
HDL cholesterol(per 1 mmol/l)* 0.740(0.242-2.267) 0.598 0.632(0.196-2.034) 0.442
ACR(mg/g) 1.000(0.999-1.000) 0.574 1.000(0.999-1.000) 0.538
baPWV(cm/sec)* 6.117(1.032-36.245) 0.046 8.496(1.216-59.348) 0.031
Diabetic retinopathy, no vs yes 1.431(0.586-3.493) 0.431 1.589(0.634-3.984) 0.323
Diabetic peripheral neuropathy, no vs yes 2.071(0.994-4.315) 0.052 2.672(1.155-6.183) 0.022
Diabetic nephropathy, no vs yes 0.940(0.426-2.072) 0.878 1.087(0.459-2.575) 0.849
  1. Data were obtained from a multivariate regression model.
  2. Model A, adjusted for age; Model B, adjusted for age, gender, smoking, drinking, duration of diabetes, BMI, HbA1c, systolic blood pressure, the presence of diabetic retinopathy.
  3. *Denotes the variables that were log-transformed when statistics were applied.