Table 4 Relationships between multiple risk factors and cardiovascular autonomic neuropathy

Age > 60 years, no vs yes

2.247(1.160-4.349)

0.016

2.837(1.365-5.897)

0.005

Gender(male)

1.513(0.776-2.951)

0.225

1.692(0.840-3.406)

0.141

Duration of diabetes(per decade)

0.848(0.474-1.517)

0.578

0.832(0.454-1.523)

0.550

BMI(per kg/m2)

0.888(0.800-0.985)

0.024

0.888(0.798-0.988)

0.029

Waist-to-hip ratio*

2.205(0.014-353.823)

0.760

2.119(0.320-14.033)

0.436

systolic blood pressure(per 10 mmHg)

1.008(0.989-1.027)

0.391

1.017(0.996-1.038)

0.108

diastolic blood pressure(per 10 mmHg)

0.997(0.966-1.028)

0.840

0.977(0.919-1.039)

0.457

Current smoker, no vs yes

1.660(0.792-3.479)

0.179

1.331(0.599-2.955)

0.482

Alcohol consumption, no vs yes

1.521(0.702-3.292)

0.287

1.474(0.660-3.293)

0.344

Hypertension, no vs yes

1.262(0.645-2.468)

0.497

1.563(0.767-3.183)

0.219

HbA1c(per 1%)

1.115(0.929-1.338)

0.244

1.091(0.905-1.314)

0.550

fasting glucose(per 1 mmol/l)*

1.020(0.922-1.128)

0.700

0.594(0.176-2.007)

0.401

Creatinine (per 1 μmol/L)*

0.954(0.230-3.950)

0.948

1.119(0.256-4.882)

0.881

eGFR( per 1 ml/min/1.73 m2)

0.999(0.987-1.011)

0.874

0.995(0.982-1.008)

0.465

total cholesterol(per 1 mmol/l)

1.046(0.807-1.355)

0.735

1.024(0.778-1.349)

0.864

Triglyceride(per 1 mmol/l)*

0.823(0.462-1.469)

0.511

0.969(0.524-1.795)

0.921

LDL cholesterol(per 1 mmol/l)*

1.405(0.426-4.634)

0.576

1.470(0.423-5.113)

0.545

HDL cholesterol(per 1 mmol/l)*

0.740(0.242-2.267)

0.598

0.632(0.196-2.034)

0.442

ACR(mg/g)

1.000(0.999-1.000)

0.574

1.000(0.999-1.000)

0.538

baPWV(cm/sec)*

6.117(1.032-36.245)

0.046

8.496(1.216-59.348)

0.031

Diabetic retinopathy, no vs yes

1.431(0.586-3.493)

0.431

1.589(0.634-3.984)

0.323

Diabetic peripheral neuropathy, no vs yes

2.071(0.994-4.315)

0.052

2.672(1.155-6.183)

0.022

Diabetic nephropathy, no vs yes

0.940(0.426-2.072)

0.878

1.087(0.459-2.575)

0.849