Table 3 Incidence and hazard ratio of nephropathy and mortality according to age and blood pressure control
Time-weighted average of SBP (mm Hg) | |||
|---|---|---|---|
<128 (1sttertile) | 128-141 (2ndtertile) | >141 (3rdtertile) | |
Aged 41–70 years (patient-years) | 129 (938) | 102 (712) | 110 (764) |
Clinical albuminuria | |||
Events and rate (per 1000 patient-years) | 12 (12.8) | 17 (23.9) | 33 (86.4) |
Adjusted hazard ratio | 1 | 1.90 (0.91–3.98) | 3.70 (1.91–7.17) |
eGFR <30 mL/[min · 1.73 m2] | |||
Events and rate (per 1000 patient-years) | 5 (5.33) | 9 (12.6) | 11 (14.4) |
Adjusted hazard ratio | 1 | 2.44 (0.81–7.29) | 2.67 (1.03–7.67) |
End-stage renal disease | |||
Events and rate (per 1000 patient-years) | 2 (2.13) | 4 (5.62) | 6 (7.85) |
Adjusted hazard ratio | 1 | 2.71 (0.49–14.88) | 3.56 (0.72–17.67) |
All-cause mortality | |||
Events and rate (per 1000 patient-years) | 13 (13.9) | 10 (14.0) | 18 (23.6) |
Adjusted hazard ratio | 1 | 1.04 (0.46–2.38) | 1.77 (1.07–3.61) |
Aged 71–85 years (patient-years) | 120 (816) | 136 (911) | 124 (860) |
Clinical albuminuria | |||
Events and rate (per 1000 patient-years) | 25 (30.6) | 33 (36.2) | 24 (27.9) |
Adjusted hazard ratio | 1 | 1.09 (0.64–1.84) | 1.03 (0.59–1.81) |
eGFR <30 mL/[min · 1.73 m2] | |||
Events and rate (per 1000 patient-years) | 26 (31.9) | 13 (14.3) | 14 (16.3) |
Adjusted hazard ratio | 1 | 0.45 (0.23–0.89) | 0.62 (0.32–1.20) |
End-stage renal disease | |||
Events and rate (per 1000 patient-years) | 10 (12.3) | 2 (2.20) | 3 (3.49) |
Adjusted hazard ratio | 1 | 0.21 (0.04–0.95) | 0.36 (0.10–1.32) |
All-cause mortality | |||
Events and rate (per 1000 patient-years) | 43 (52.9) | 33 (36.2) | 29 (33.7) |
Adjusted hazard ratio | 1 | 0.68 (0.43–1.09) | 0.64 (0.40–1.03) |