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Table 1 Baseline characteristics according to the age groups in type 2 diabetic patients

From: Effects of glucose and blood pressure control on diabetic kidney disease in old patients with type 2 diabetes

  41-60 years 61-70 years 71-75 years 76-85 years P value
Number 184 157 194 186  
Age (years) 52.3 ± 5.4 66.7 ± 2.8 72.9 ± 1.4 77.9 ± 2.0 <0.001
Sex (men/women) 85/99 84/73 160/34 167/19 <0.001
Diabetes duration (years) 6.4 ± 5.7 9.4 ± 7.2 11.6 ± 8.6 12.3 ± 8.3 0.001
Current smokers (%) 19.3 16.9 20.4 17.9 0.851
BMI (Kg/m2) 26.2 ± 4.2 26.0 ± 3.5 25.4 ± 3.4 24.7 ± 3.1 0.004
Systolic blood pressure (mmHg) 137.2 ± 17.2 141.8 ± 18.7 143.3 ± 19.2 141.5 ± 18.5 0.070
Diastolic blood pressure (mmHg) 82.3 ± 10.3 78.3 ± 11.2 75.2 ± 10.5 72.3 ± 10.6 0.001
Fasting plasma glucose (mg/dL) 163.4 ± 48.4 164.7 ± 44.7 161.0 ± 44.8 164.3 ± 41.3 0.876
HbA1c (%) 8.00 ± 1.81 7.91 ± 1.66 7.88 ± 1.62 7.77 ± 1.53 0.624
Total cholesterol (mg/dL) 204.9 ± 40.2 197.3 ± 38.5 198.4 ± 36.4 191.2 ± 39.0 0.051
High density cholesterol (mg/dL) 34.3 ± 9.2 37.6 ± 5.9 47.6 ± 8.9 45.3 ± 12.3 0.013
Triglyceride (mg/dL), median (interquartile range) 160 (98-233) 145 (96-220) 125 (86-191) 123 (85-194) 0.071
Serum creatinine (mg/dL) 1.03 ± 0.32 1.15 ± 0.46 1.22 ± 0.40 1.30 ± 0.52 0.001
eGFR (mL/min per1.73 m2) 75.5 ± 23.1 65.1 ± 17.7 64.6 ± 20.5 60.8 ± 17.2 0.001
Urine albumin-to-creatinine ratio (mg/g), median (interquartile range) 17.5 (7.5-115.7) 18.8 (8.1-113.8) 31.6 (11.0-125.1) 24.6 (12.9-106.7) 0.293
Glucose lowering treatment      
 Insulin (%) 35.1 29.3 40.2 26.0 0.150
 Sulfonylureas (%) 62.6 69.9 61.5 57.3 0.339
 Metformin (%) 73.3 70.7 64.1 57.3 0.069
 Thiazolidinediones (%) 13.0 15.4 8.5 8.3 0.383
 Other (%) 10.7 14.6 17.1 10.4 0.354
Cardiovascular medication      
 ACE inhibitor or ARB (%) 48.1 50.4 59.8 59.3 0.110
 Calcium channel blocker (%) 33.6 44.7 51.3 61.5 0.007
 Beta-blocker (%) 28.2 26.8 29.9 34.4 0.658
 Diuretics (%) 16.0 24.4 33.3 24.6 0.183
 Statin (%) 29.8 28.5 21.4 15.6 0.064
 Fibrate (%) 2.3 3.1 1.0 2.1 0.143
 Aspirin (%) 23.7 32.5 43.6 43.8 0.002
  1. Abbreviations: BMI Body mass index, HbA1c Glycated hemoglobin, ACE Angiotensin converting enzyme, ARB Angiotensin receptor blocker.