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Table 2 Linear and logistic regression analyses for the effect of cigarette smoking on Hs-CRP and interaction with metabolic syndrome

From: Cigarette smoking worsens systemic inflammation in persons with metabolic syndrome

Median linear regression coefficients (95% CI)

 

Total

MetS absent

MetS present

P interaction

Model 1

0.20 (0.07, 0.33)

0.10(-0.04, 0.24)

0.60 (0.23, 0.97)

0.002

Model 2

0.18 (0.04, 0.32)

0.11 (-0.04, 0.26)

0.60 (0.10, 1.01)

0.001

Model 3

0.19 (0.05, 0.32)

0.09 (-0.05, 0.24)

0.63 (0.26, 1.01)

0.001

Logistic regression odds ratio for elevated hs-CRP (95% CI)

 

Total

MetS absent

MetS present

P interaction

Model 1

1.54 (1.25, 1.91)

1.27 (0.97, 1.66)

2.02 (1.39, 2.93)

0.049

Model 2

1.55 (1.26, 1.93)

1.28 (0.97, 1.67)

2.05 (1.40, 2.99)

0.05

Model 3

1.55 (1.25, 1.92)

1.29 (0.98, 1.69)

2.05 (1.40, 3.01)

0.076

  1. Model 1: unadjusted; Model 2: adjusted for age and sex; and Model 3: adjusted for age, sex, LDL, total cholesterol, statins and anti-hypertensive medications hs-CRP: high sensitivity C-reactive protein; and MetS: metabolic syndrome elevated hs-CRP = hs-CRP >3 mg/L.