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Table 3 Characteristics of patients with FCHL included in the longitudinal study before and after treatment for their dyslipidemia

From: Vitamin D concentrations in familial combined hyperlipidemia: effects of lipid lowering treatment

 

Off- treatment

With treatment

P

25(OH)D (nmol/L)

51.0 ± 31.3

58.9 ± 24.6

0.022

BMI (Kg/m2)

26.6 ± 2.6

26.6 ±2.6

0.778

Waist (cm)

92.7 ± 9.2

93.1 ± 8.8

0.518

HOMA

2.0 ± 1.1

2.2 ± 1.4

0.535

Total cholesterol (mmol/L)

7.4 (5.1-16.1)

5.1 (3.8-8.9)

0.000

Triglycerides (mmol/L)

2.8 (1.2-10.7)

1.9 (0.8-3.8)

0.000

LDL-c (mmol/L)

4.3 (1.4-7.8)

3.0 (2.0-5.8)

0.007

HDL-c (mmol/L)

1.2 ± 0.4

1.3 ± 0.3

0.000

VLDL-c (mmol/L)

1.3 (0.6-8.6)

0.9 (0.4-3.3)

0.000

NEFA (mmol/L)

0.6 (0.3-1.6)

0.6 (0.3-1.4)

0.313

ApoB (g/L)

1.4 ± 0.3

1.0 ± 0.2

0.000

LDLsize (nm)

25.3 (23.2-26.2)

25.7 (24.8-26.5)

0.058

CRP (mg/L)

2.0 (0.1-21.1)

1.3 (0.3-12.2)

0.823

  1. P values according to paired T-test and Wilcoxon test.
  2. FCHL: Familial combined hyperlipidemia, 25(OH)D: 25-hydroxyvitamin D, BMI: body mass index, HOMA: homeostasis model assessment, LDL-c: low-density lipoprotein cholesterol, HDL-c: high-density lipoprotein cholesterol, VLDL-c: very low-density lipoprotein cholesterol, LDL: low-density lipoprotein, NEFA: non-esterified fatty acids, ApoB: apolipoprotein B, CRP: C-reactive protein.