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Table 1 Clinical and biochemical characteristics of patients with FCHL and control subjects

From: Vitamin D concentrations in familial combined hyperlipidemia: effects of lipid lowering treatment

 

Cases (n = 59)

Controls (n = 48)

P

Age (years)

50.2 ± 11.6

46.5 ± 17.2

0.210

Sex (% men)

57.6

62.5

0.609

BMI (Kg/m2)

27.9 ± 4.1

25.4 ± 4.1

0.005

Waist (cm)

  

0.026

- Men

97.7 ± 9

91.79 ± 12.1

- Women

92.7 ± 12.4

88.8 ± 11.8

Glucose (mmol/L)

5.3 ± 0.6

4.9 ± 0.73

0.020

HbA1c (%)

5.6 ± 0.5

5.4 ± 0.6

0.135

Total cholesterol (mmol/L)

6.7 ± 1.6

4.8 ± 0.8

0.000

Triglycerides (mmol/L)

2.3 (1.1-15.8)

0.7 (0.3-2.1)

0.000

LDL-c (mmol/L)

4.1 ± 1.3

2.8 ± 0.7

0.000

HDL-c (mmol/L)

1.2 ± 0.4

1.6 ± 0.4

0.000

VLDL-c (mmol/L)

1.0 (0.5-7.6)

0.4 (0.1-1.2)

0.000

NEFA (mmol/L)

0.7 (0.2-4.3)

0.4 (0.1-1.1)

0.000

ApoB (g/L)

1.3 ± 0.3

0.8 ± 0.2

0.000

CRP (mg/L)

1.6 (0.2-21.5)

1.0 (0.2-15.0)

0.133

25(OH)D (nmol/L)

58.9 ± 24.5

69.1 ± 30.0

0.057

  1. P values according to T-test and Mann–Whitney test.
  2. FCHL: Familial combined hyperlipidemia, BMI: body mass index, HbA1c: glicated haemoglobin, LDL-c: low-density lipoprotein cholesterol, HDL-c: high-density lipoprotein cholesterol, VLDL-c: very low-density lipoprotein cholesterol, NEFA: non-esterified fatty acids, ApoB: apolipoprotein B, CRP: C-reactive protein, 25(OH)D: 25-hydroxyvitamin D.