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Table 3 Adverse events

From: Efficacy and safety of vildagliptin, Saxagliptin or Sitagliptin as add-on therapy in Chinese patients with type 2 diabetes inadequately controlled with dual combination of traditional oral hypoglycemic agents

Adverse event Saxagliptin n = 68 Vildagliptin n = 63 Sitagliptin n = 63 P value
Edema 1(2%) 0(0%) 1(2%) 0.60
Headache 0(0%) 1(2%) 1(2%) 0.58
Elevated liver enzymes 2(3%) 3(5%) 2(3%) 0.86
Symptomatic hypoglycemia 4(6%) 1(2%) 2(3%) 0.41
Abdominal discomfort 3(4%) 5(8%) 3(5%) 0.64
Diarrhea 3(4%) 1(2%) 3(5%) 0.57
Chest discomfort & dyspnea 2(3%) 2(3%) 2(3%) 0.99
Nasosinusitis 5(7%) 0(0%) 6(10%) 0.053
Total 20(29%) 13(21%) 20(32%)  
  1. Data are presented as number (%). χ2 test and Fisher’s exact test were used for comparison of differences in the three groups.