Table 2 Changes of variables related with HbA 1c , FBG, and P2hBG after 24-week treatment
Baseline (mean ± s.d) | 24 weeks (mean ± s.d) | Mean changes from baseline (95% CI) | ★Difference in mean change (95% CI) | ΔDifference in mean change (95% CI) | |
|---|---|---|---|---|---|
HbA1c (%) | |||||
Vildagliptin | 8.75 ± 1.15 | 7.41 ± 1.43 | -1.34 (-2.03, -0.64)** | ||
Saxagliptin | 8.86 ± 1.13 | 7.65 ± 1.41 | -1.21 (-1.91, -0.51)** | 0.13 (-0.66, 0.40) | |
Sitagliptin | 8.54 ± 1.19 | 7.47 ± 1.42 | -1.07 (-1.64, -0.50)** | 0.27 (-0.80, 0.26) | 0.14 (-0.67, 0.39) |
FBG (mmol/L) | |||||
Vildagliptin | 8.79 ± 1.80 | 6.35 ± 1.57 | -2.44 (-3.01, -1.87)** | ||
Saxagliptin | 8.36 ± 2.04 | 6.53 ± 1.92 | -1.83 (-2.13, -1.53)** | 0.61 (0.30, 0.92)## | |
Sitagliptin | 8.22 ± 1.77 | 6.73 ± 1.69 | -1.49 (-1.69, -1.29)** | 0.95 (0.64, 1.26)## | 0.34 (0.03, 0.65)Δ |
P2BG (mmol/L) | |||||
Vildagliptin | 11.98 ± 2.46 | 8.27 ± 2.28 | -3.71 (-4.16, -3.26)** | ||
Saxagliptin | 11.77 ± 3.07 | 8.36 ± 2.70 | -3.41 (-4.33, -2.49)** | 0.30 (-0.32, 0.92) | |
Sitagliptin | 10.98 ± 2.93 | 7.82 ± 2.58 | -3.16 (-4.03, -2.29)** | 0.55 (-0.07, 1.17) | -0.25 (-0.37, 0.87) |