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Table 1 Demographic and baseline characteristics

From: Efficacy and safety of vildagliptin, Saxagliptin or Sitagliptin as add-on therapy in Chinese patients with type 2 diabetes inadequately controlled with dual combination of traditional oral hypoglycemic agents

 

Total n = 190

Saxagliptin n = 66

Vildagliptin n = 63

Sitagliptin n = 61

p value

Age (years), mean ± SD

46.6 ± 9.0

46.5 ± 10.7

44.8 ± 8.5

48.6 ± 11.3

0.90

Range

23 ~ 72

23 ~ 72

25 ~ 63

29 ~ 70

-

Age (years), n (%)

<50 years

53(28%)

18(27%)

18(29%)

17(27%)

0.99

50 ~ 65 years

90(47%)

31(47%)

29(46%)

30(50%)

0.94

>65 years

47(25%)

17(26%)

16(25%)

14(23%)

0.93

Gender, n (%)

Male

109(57%)

39(59%)

37(59%)

33(54%)

0.82

Female

81(43%)

27(41%)

26(41%)

28(46%)

0.82

Duration of diabetes (years), n (%)

<1 year

61(32%)

20(30%)

24(38%)

17(28%)

0.44

1 ~ 5 years

69(36%)

24(37%)

21(33%)

24(40%)

0.79

>5 years

60(32%)

22(33%)

18(29%)

20(32%)

0.82

Body weight (kg), mean ± SD

74.4 ± 11.1

77.2 ± 15.1

72.7 ± 11.3

73.2 ± 10.9

0.89

BMI (kg/m2), mean ± SD

26.3 ± 2.8

26.9 ± 3.1

25.3 ± 2.8

26.6 ± 3.3

0.80

HbA1c (%), mean ± SD

8.72 ± 1.01

8.86 ± 1.13

8.75 ± 1.15

8.54 ± 1.19

0.94

FBG (mmol/l), mean ± SD

8.46 ± 1.61

8.36 ± 2.04

8.79 ± 1.80

8.22 ± 1.77

0.93

P2hBG(mmol/l), mean ± SD

11.58 ± 2.49

11.77 ± 3.07

11.98 ± 2.46

10.98 ± 2.93

0.90

Therapy, n (%)

Metformin with glimepiride

77(41%)

26(40%)

26(41%)

25(41%)

0.97

Metformin with acarbose

62(33%)

22(33%)

20(32%)

20(33%)

0.98

Metformin with pioglitazone

51(26%)

18(27%)

17(27%)

16(26%)

0.99

  1. Abbreviations: BMI body mass index; FBG fasting blood glucose; P2hBG postprandial 2 hours’ blood glucose.
  2. Data are presented as mean ± standard deviation, as well as, n and%.