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Table 9 Histomorphometric parameters of the thoracic aortas

From: Angiotensin II receptor blocker telmisartan attenuates aortic stiffening and remodelling in STZ-diabetic rats

Parameter

Control

Diabetes

Diabetes + telmisartan

Internal diameter of aorta (mm)

1.65 ± 0.18

1.23 ± 0.19¶

1.54 ± 0.22#

Width of media (μm)

117.39 ± 16.30

82.62 ± 9.32¶

87.68 ± 11.11¶

Elastic fibres in media (arbitrary units)

2.84 ± 0.23

2.54 ± 0.34*

2.65 ± 0.27

Collagen fibres in media (arbitrary units)

0.66 ± 0.19

1.43 ± 0.31¶

1.30 ± 0.10¶

Elastin/collagen ratio in media (%)

4.28 ± 0.57

1.79 ± 0.035¶

2.07 ± 0.50*

Smooth muscle cell nuclei

78.86 ± 15.01

94.10 ± 21.12

89.17 ± 24.90

CML (arbitrary units)

0.53 ± 0.08

2.28 ± 1.05¶

1.55 ± 0.80¶

  1. Values are expressed as means ± SD. CML, N ϵ-(carboxymethyl) lysine.
  2. *P <0.05 vs Control; ¶P <0.001 vs Control; #P <0.05 vs Diabetes.