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Table 9 Histomorphometric parameters of the thoracic aortas

From: Angiotensin II receptor blocker telmisartan attenuates aortic stiffening and remodelling in STZ-diabetic rats

Parameter Control Diabetes Diabetes + telmisartan
Internal diameter of aorta (mm) 1.65 ± 0.18 1.23 ± 0.19 1.54 ± 0.22#
Width of media (μm) 117.39 ± 16.30 82.62 ± 9.32 87.68 ± 11.11
Elastic fibres in media (arbitrary units) 2.84 ± 0.23 2.54 ± 0.34* 2.65 ± 0.27
Collagen fibres in media (arbitrary units) 0.66 ± 0.19 1.43 ± 0.31 1.30 ± 0.10
Elastin/collagen ratio in media (%) 4.28 ± 0.57 1.79 ± 0.035 2.07 ± 0.50*
Smooth muscle cell nuclei 78.86 ± 15.01 94.10 ± 21.12 89.17 ± 24.90
CML (arbitrary units) 0.53 ± 0.08 2.28 ± 1.05 1.55 ± 0.80
  1. Values are expressed as means ± SD. CML, N ϵ-(carboxymethyl) lysine.
  2. *P <0.05 vs Control; P <0.001 vs Control; #P <0.05 vs Diabetes.