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Table 1 Demographic and Clinical Characteristics of the Analytic Sample

From: The association of body mass index with the risk of type 2 diabetes: a case–control study nested in an electronic health records system in the United States

 

Cases

Controls

P value

(With T2D) N = 12,179

(Without diabetes) N = 25,177

BMI (mean ± SD, kg/m2)

35.4 ± 8.5

29.4 ± 6.3

<0.01

BMI category (%)

  

<0.01

 18.5–24.9 kg/m2

7.4

24.1

 

 25.0–29.9 kg/m2

20.5

36.1

 

 30.0–34.9 kg/m2

26.3

23.3

 

 35.0–39.9 kg/m2

20.6

10.0

 

 40+ kg/m2

25.3

6.5

 

Age (mean ± SD)

55 ± 15.9

56 ± 18.2

<0.01

Age group (%)

  

<0.01

 18.5–24.9

25.0

27.6

 

 25.0–29.9

45.2

34.2

 

 30.0–34.9

17.5

20.8

 

 35.0–39.9

10.3

13.7

 

 40+

2.0

3.7

 

Male (%)

42.9

44.6

<0.01

Race (%)

  

<0.01

 White

97.1

97.5

 

 Black

1.8

1.3

 

 Other/unknown

1.1

1.2

 

Index year (%)

  

<0.01

 2005

8.8

10.0

 

 2006

13.0

10.9

 

 2007

15.3

12.2

 

 2008

15.5

14.1

 

 2009

18.9

16.2

 

 2010

16.4

18.8

 

 2011

12.0

17.8

 

Smoking status (%)

  

<0.01

 Never smoke

49.0

48.0

 

 Former smoker

29.8

22.6

 

 Current smoker

17.8

15.4

 

 Other/unknown

3.4

14.0

 

Employment status (%)

  

<0.01

 Full Time

37.1

32.4

 

 Not employed

22.2

15.5

 

 Other/unknown

40.8

52.1

 

Payer status (%)

  

<0.01

 Commercial

78.9

72.4

 

 Medicare

12.8

14.1

 

 Medicaid

4.6

3.1

 

 Other/unknown

3.6

10.4

 

Covered by Geisinger Health Plan (%)

49.7

43.8

<0.01

Any cardiac comorbidities (%)

85.3

63.1

<0.01

Hyperinflammatory state (%)

6.3

2.1

<0.01

Depression (%)

8.2

4.1

<0.01

Psychiatric drugs (%)

14.7

7.7

<0.01

Antidepressants/anxiolytics (%)

36.5

22.4

<0.01

Anti-obesity drugs (%)

0.4

0.1

<0.01

Beta blockers (%)

32.3

21.4

<0.01

Antihyperlipidemia drugs (%)

36.7

23.1

<0.01

Antihypertensives (%)

35.2

21.1

<0.01

Any outpatient encounters (%)

95.8

88.3

<0.01

Any inpatient encounters (%)

16.6

7.9

<0.01

Any emergency department encounters (%)

14.3

8.8

<0.01

Total encounter costs ($,mean ± SD)

6,324 ± 17,253

2,640 ± 7,606

<0.01

  1. Data source: Geisinger Health System electronic health records, January 2004–October 2011.
  2. Characteristics were measured at index date or during 1 year before index date.
  3. Any cardiac comorbidities: lipid abnormalities, coronary heart disease, acute myocardial infarction, angina pectoris, and hypertension, were defined by both ICD-9-CM diagnosis codes and clinical biomarkers.
  4. Hyperinflammatory state: defined by clinical biomarkers of C-reactive protein and erythrocyte sedimentation rate.
  5. Psychiatric medication use: anticonvulsants or antipsychotic medication.
  6. Total encounter costs: in 2011 dollars.
  7. P value based on t-test for continuous variables and chi-squared test for categorical variables.