Cases | Controls | P value | |
---|---|---|---|
(With T2D) N = 12,179 | (Without diabetes) N = 25,177 | ||
BMI (mean ± SD, kg/m2) | 35.4 ± 8.5 | 29.4 ± 6.3 | <0.01 |
BMI category (%) | <0.01 | ||
18.5–24.9 kg/m2 | 7.4 | 24.1 | |
25.0–29.9 kg/m2 | 20.5 | 36.1 | |
30.0–34.9 kg/m2 | 26.3 | 23.3 | |
35.0–39.9 kg/m2 | 20.6 | 10.0 | |
40+ kg/m2 | 25.3 | 6.5 | |
Age (mean ± SD) | 55 ± 15.9 | 56 ± 18.2 | <0.01 |
Age group (%) | <0.01 | ||
18.5–24.9 | 25.0 | 27.6 | |
25.0–29.9 | 45.2 | 34.2 | |
30.0–34.9 | 17.5 | 20.8 | |
35.0–39.9 | 10.3 | 13.7 | |
40+ | 2.0 | 3.7 | |
Male (%) | 42.9 | 44.6 | <0.01 |
Race (%) | <0.01 | ||
White | 97.1 | 97.5 | |
Black | 1.8 | 1.3 | |
Other/unknown | 1.1 | 1.2 | |
Index year (%) | <0.01 | ||
2005 | 8.8 | 10.0 | |
2006 | 13.0 | 10.9 | |
2007 | 15.3 | 12.2 | |
2008 | 15.5 | 14.1 | |
2009 | 18.9 | 16.2 | |
2010 | 16.4 | 18.8 | |
2011 | 12.0 | 17.8 | |
Smoking status (%) | <0.01 | ||
Never smoke | 49.0 | 48.0 | |
Former smoker | 29.8 | 22.6 | |
Current smoker | 17.8 | 15.4 | |
Other/unknown | 3.4 | 14.0 | |
Employment status (%) | <0.01 | ||
Full Time | 37.1 | 32.4 | |
Not employed | 22.2 | 15.5 | |
Other/unknown | 40.8 | 52.1 | |
Payer status (%) | <0.01 | ||
Commercial | 78.9 | 72.4 | |
Medicare | 12.8 | 14.1 | |
Medicaid | 4.6 | 3.1 | |
Other/unknown | 3.6 | 10.4 | |
Covered by Geisinger Health Plan (%) | 49.7 | 43.8 | <0.01 |
Any cardiac comorbidities (%) | 85.3 | 63.1 | <0.01 |
Hyperinflammatory state (%) | 6.3 | 2.1 | <0.01 |
Depression (%) | 8.2 | 4.1 | <0.01 |
Psychiatric drugs (%) | 14.7 | 7.7 | <0.01 |
Antidepressants/anxiolytics (%) | 36.5 | 22.4 | <0.01 |
Anti-obesity drugs (%) | 0.4 | 0.1 | <0.01 |
Beta blockers (%) | 32.3 | 21.4 | <0.01 |
Antihyperlipidemia drugs (%) | 36.7 | 23.1 | <0.01 |
Antihypertensives (%) | 35.2 | 21.1 | <0.01 |
Any outpatient encounters (%) | 95.8 | 88.3 | <0.01 |
Any inpatient encounters (%) | 16.6 | 7.9 | <0.01 |
Any emergency department encounters (%) | 14.3 | 8.8 | <0.01 |
Total encounter costs ($,mean ± SD) | 6,324 ± 17,253 | 2,640 ± 7,606 | <0.01 |