Table 1 Demographic characteristics
Valvar (n = 20) | P* value | CAD/MS group | |||||
|---|---|---|---|---|---|---|---|
Control (n = 17) | Simvastatin (n = 20) | Pioglitazone (n = 18) | Pioglitazone + Simvastatin (n = 18) | P** value | |||
Age (yrs) | 52.3 ± 8.0 | <0.001 | 64.3 ± 6.06 | 60.1 ± 6.38 | 57.6 ± 5.89 | 60.1 ± 7.08 | 0.024 |
Male (%) | 6(30) | 0.005 | 12(70.6) | 16(80) | 10 (55.6) | 10 (55.6) | 0.314 |
Waist circumference (cm) | 78.4 ± 11.9 | <0.001 | 103.6 ± 6.43 | 103.2 ± 8.62 | 103.7 ± 8.09 | 105.2 ± 9.06 | 0.883 |
Systolic BP (mmHg) | 113 ± 10.3 | <0.001 | 145 ± 17.1 | 134 ± 15.1 | 162 ± 20.3 | 145 ± 13.8 | <0.001 |
Diastolic BP (mmHg) | 72 ± 11.5 | 0.006 | 87 ± 11.8 | 78 ± 10.3 | 85 ± 12 | 73 ± 11.2 | 0.001 |
Baseline Weight (Kg) | 58.9 ± 12.4 | <0.001 | 85.8 ± 13.7 | 76.7 ± 10.8 | 80.6 ± 13.7 | 83.9 ± 10.2 | 0.122 |
Final Weight (Kg) | 57.2 ± 11.9 | <0.001 | 82.5 ± 12.9 | 74.6 ± 10.5 | 81.4 ± 14.6 | 83.3 ± 9.3 | 0.102 |