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Figure 2 | Diabetology & Metabolic Syndrome

Figure 2

From: Synergistic anti-inflammatory effect: simvastatin and pioglitazone reduce inflammatory markers of plasma and epicardial adipose tissue of coronary patients with metabolic syndrome

Figure 2

Immunohistochemical staining in the EAT: components. (A) Immunohistochemical staining for inflammatory cells in the EAT. CD68+: macrophages; CD45 T: T-lymphocytes; CD20 B: B-lymphocytes; TNF-α: tumoral necrosis factor alpha; IL-6: interleukin 6. CD45 T and CD20 B cells formed inflammatory clusters close to the edge of and around vessels of the EAT sections in the simvastatin group, but the center of the fat fragment was free of inflammatory cells. 200X. See text for details. (B) Immunohistochemical staining for pro- and anti-inflammatory cytokines in the EAT. CD68+: macrophages; CD45 T: T-lymphocytes; CD20 B: B-lymphocytes; TNF-α: tumoral necrosis factor alpha; IL-6: interleukin 6. CD45 T and CD20 B cells formed inflammatory clusters close to the edge of and around vessels of the EAT sections in the simvastatin group, but the center of the fat fragment was free of inflammatory cells. 200X. See text for details.

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