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Table 1 Clinical and laboratory features of patients with diabetes and normal glucose tolerance, according to the presence of CAD

From: Association of classical risk factors and coronary artery disease in type 2 diabetic patients submitted to coronary angiography

 

Normoglycemic individuals

 

Diabetic individuals

 
 

Without CAD

With DAC

p**

Without CAD

With CAD

p**

N

40

54

 

110

237

 

Age (years)

55.8 (12.9)

60.2 (13.6)

NS

59.1 (10.2)

61.6 (9.8)

0.03

Male gender (%)

53.7

76.4

0.02

40

61.2

0.001

BMI (kg/m2)

27.1 (5.24)

26.4 (4.91)

NS

29.2 (5.32)

28.0 (4.40)

0.04

Abdominal circumference (cm)

95.5 (12.9)

97.0 (12.4)

NS

101.9 (12.65)

100.5 (12.00)

NS

Diabetes duration (years)*

4 [1-10]

6 [2-10]

NS

SBP (mmHg)

134.4 (21.8)

131.9 (22.6)

NS

145.2 (24.6)

142.3 (24.6)

NS

DBP (mmHg)

79.0 (15.4)

79.7 (14.2)

NS

82.4 (16.1)

79.2 (12.1)

NS

FPG (mg/dl)

90.4 (6.8)

90.8 (7.1)

NS

143.4 (48.9)

162.3 (69.8)

0.004

Fasting insulin (mU/L)

6.44 (4.38)

6.10 (4.77)

NS

14.6 (17.6)

10.9 (8.91)

NS

HOMA2B

69.17 (25.63)

66.50 (25.82)

NS

75.56 (51.83)

64.07 (48.51)

NS

HOMA2-IR

0.70 (0.41)

0.66 (0.42)

NS

1.84 (1.67)

1.54 (1.03)

NS

HbA1c (%)

5.28 (0.27)

5.35 (0.25)

NS

7.59 (1.55)

8.03 (1.91)

0.03

LDL (mg/dL)

105.0 (34.8)

98.6 (33.4)

NS

101.0 (39.9)

98.1 (36.2)

NS

HDL (mg/dL)

42.7 (11.4)

38.4 (10.340

NS

44.4 (15.9)

39.2 (13.2)

0.003

Triglycerides (mg/dL)*

116.0 [75.25-158.0]

115.0 [93.0-158.0]

NS

121.0 [78.5-184.25]

140.0 [106.0-204.0]

0.002

Total Adiponectin (μg/mL)*

11.80 [6.85-18.62]

8.73 [5.95-14.88]

NS

8.26 [5.49-12.86]

7.36 [5.33-11.83]

NS

eGFR (mL/min)

88.1 (22.3)

83.6 (21.4)

NS

83.1 (28.3)

80.4 (24.2)

NS

Hypertension (%)

73.2

72.7

NS

95.5

94.5

NS

Framingham risk above 20% (%)

8.6

17

NS

21.6

32.5

0.047

Statin use (%)

41.5

56.4

NS

60.9

72.6

0.03

Aspirin use (%)

58.5

67.3

NS

70

79.7

0.046

Diabetes treatment

      

Insulin (%)

24.5

28.3

NS

Sulphonylurea (%)

20.4

27

NS

Metformin (%)

44.5

45.6

NS

Dyslipidemia (%)

70.7

89.1

0.023

89.1

90.3

NS

Familial history of CAD (%)

29.3

45.5

NS

34.9

35

NS

  1. Values expressed in mean (SD), except where otherwise noted; *values expressed in median [interquartile range]; **p values for comparisons between individuals with and without CAD, within diabetic and normoglycemic groups.