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Table 1 Clinical and laboratory features of patients with diabetes and normal glucose tolerance, according to the presence of CAD

From: Association of classical risk factors and coronary artery disease in type 2 diabetic patients submitted to coronary angiography

  Normoglycemic individuals   Diabetic individuals  
  Without CAD With DAC p** Without CAD With CAD p**
N 40 54   110 237  
Age (years) 55.8 (12.9) 60.2 (13.6) NS 59.1 (10.2) 61.6 (9.8) 0.03
Male gender (%) 53.7 76.4 0.02 40 61.2 0.001
BMI (kg/m2) 27.1 (5.24) 26.4 (4.91) NS 29.2 (5.32) 28.0 (4.40) 0.04
Abdominal circumference (cm) 95.5 (12.9) 97.0 (12.4) NS 101.9 (12.65) 100.5 (12.00) NS
Diabetes duration (years)* 4 [1-10] 6 [2-10] NS
SBP (mmHg) 134.4 (21.8) 131.9 (22.6) NS 145.2 (24.6) 142.3 (24.6) NS
DBP (mmHg) 79.0 (15.4) 79.7 (14.2) NS 82.4 (16.1) 79.2 (12.1) NS
FPG (mg/dl) 90.4 (6.8) 90.8 (7.1) NS 143.4 (48.9) 162.3 (69.8) 0.004
Fasting insulin (mU/L) 6.44 (4.38) 6.10 (4.77) NS 14.6 (17.6) 10.9 (8.91) NS
HOMA2B 69.17 (25.63) 66.50 (25.82) NS 75.56 (51.83) 64.07 (48.51) NS
HOMA2-IR 0.70 (0.41) 0.66 (0.42) NS 1.84 (1.67) 1.54 (1.03) NS
HbA1c (%) 5.28 (0.27) 5.35 (0.25) NS 7.59 (1.55) 8.03 (1.91) 0.03
LDL (mg/dL) 105.0 (34.8) 98.6 (33.4) NS 101.0 (39.9) 98.1 (36.2) NS
HDL (mg/dL) 42.7 (11.4) 38.4 (10.340 NS 44.4 (15.9) 39.2 (13.2) 0.003
Triglycerides (mg/dL)* 116.0 [75.25-158.0] 115.0 [93.0-158.0] NS 121.0 [78.5-184.25] 140.0 [106.0-204.0] 0.002
Total Adiponectin (μg/mL)* 11.80 [6.85-18.62] 8.73 [5.95-14.88] NS 8.26 [5.49-12.86] 7.36 [5.33-11.83] NS
eGFR (mL/min) 88.1 (22.3) 83.6 (21.4) NS 83.1 (28.3) 80.4 (24.2) NS
Hypertension (%) 73.2 72.7 NS 95.5 94.5 NS
Framingham risk above 20% (%) 8.6 17 NS 21.6 32.5 0.047
Statin use (%) 41.5 56.4 NS 60.9 72.6 0.03
Aspirin use (%) 58.5 67.3 NS 70 79.7 0.046
Diabetes treatment       
Insulin (%) 24.5 28.3 NS
Sulphonylurea (%) 20.4 27 NS
Metformin (%) 44.5 45.6 NS
Dyslipidemia (%) 70.7 89.1 0.023 89.1 90.3 NS
Familial history of CAD (%) 29.3 45.5 NS 34.9 35 NS
  1. Values expressed in mean (SD), except where otherwise noted; *values expressed in median [interquartile range]; **p values for comparisons between individuals with and without CAD, within diabetic and normoglycemic groups.