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Table 1 Characteristics of the 25 patients at baseline and at follow up (8 weeks of treatment)

From: Fenofibrate improves endothelial function and plasma myeloperoxidase in patients with type 2 diabetes mellitus: an open-label interventional study

Variables

Visit 1 (Pre-treatment)

Visit 2 (Post treatment)

p

Age (years)

59.2 [55.2; 63.2]

-

 

Male gender (%)

13.0 (52.0%)

-

 

Current smoker

4.0 (16.0%)

-

 

Hypertension

19.0 (76.0%)

-

 

Cardiovascular disease

5.0 (20.0%)

-

 

Ischemic heart disease

4.0 (16.0%)

-

 

Ischemic stroke

1.0 (4%)

-

 

Medication

   

ACEI

10.0 (40.0%)

-

 

β-Adrenergic receptor blocker

8.0 (32.0%)

-

 

Diuretics

8.0 (32.0%)

-

 

Calcium channel blocker

7.0 (28.0%)

-

 

Angiotensin receptor blocker

4.0 (16.0%)

-

 

Aspirin

7.0 (28.0%)

-

 

SBP (mmHg)

149.8 [143.5; 156.1]

142.7 [137.6; 147.8]

0.04

DBP (mmHg)

91.5 [87.4; 95.5]

87.5 [82.8; 92.2]

0.02

BMI (kg/m2)

28.7 [26.6; 34.2]a

28.7 [26.7; 34.0]a

0.79

Waist (cm)

108.5 [104.0; 113.0]

110.4 [105.5; 115.3]

0.06

FPG (mg/dl)

136.9 [129.0; 144.8]

137.6 [129.7; 145.5]

0.82

HbA1c (%)

6.5 [6.3; 6.8]

6.5 [6.3; 6.7]

0.53

Lipids

   

Total cholesterol (mg/dl)

182.0 [166.0; 220.0]a

168.0 [151.0; 192.5]a

0.01

HDL cholesterol (mg/dl)

45.0 [40.1; 50.0]

44.1 [37.7; 50.5]

0.88

LDL-cholesterol (mg/dl)

104.0 [93.0; 139.3]a

102.0 [89.1; 125.6]a

0.14

Triglycerides (mg/dl)

168.6 [140.2; 197.0]

114.1 [95.4; 132.8]

<0.001

eGFR (ml/min/1.73 m2)

107.7 [93.4; 122.0]

96.8 [82.6; 111.1]

0.007

TGO (IU/L)

20.0 [15.5; 25.0]a

22.0 [18.0; 26.0]a

0.10

TGP (IU/L)

22.0 [17.0; 27.0]a

24.0 [20.0; 28.0]a

0.48

  1. Data in table are presented as mean [95%CI] for continuous variables, median [1st quartile; 3rd quartile] for variables with abnormal distribution and number (%) for categorical variables; a- abnormal distribution; BMI - body mass index; HbA1c – glycosilated hemoglobin; SBP –systolic blood pressure; DBP – diastolic blood pressure; FPG – fasting plasma glucose; eGFR- estimated glomerular filtration rate.