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Table 2 Prescription of drug classes for patients aged ≥45 years with diagnoses of AF and diabetes mellitus ( n= 2,413) in primary care attending the 75 PHCCs between January 1st2001 and December 31st2007

From: Effects of prescribed antithrombotics and other cardiovascular pharmacotherapies on all-cause mortality in patients with diabetes and atrial fibrillation – a cohort study from Sweden using propensity score analyses

 

Men n = 1,319

Women n = 1,094

Sex difference

 

n(%)

n(%)

p

All antithrombotic agents (B01A)

1,223 (92.7)

978 (89.4)

0.005

 Anticoagulant agents (B01AA)

806 (61.1)

567 (51.8)

<0.001

 Antiplatelet agents (B01AC)

822 (62.3)

688 (62.9)

0.77

  ASA (B01AC6, B01AC30)

800 (60.7)

672 (61.4)

0.70

Antithrombotic treatment group:

   

 No antithrombotic agent

96 (7.3)

116 (10.6)

0.004

Antiplatelets only

417 (31.6)

410 (37.5)

0.003

 Anticoagulants only

401 (30.4)

290 (26.5)

0.035

 Both antiplatelets and anticoagulants

405 (30.7)

278 (25.4)

0.004

Digitalis (C01A)

521 (39.5)

596 (54.5)

<0.001

Specific anti-arrhythmic agents (C01B)

40 (3.0)

17 (1.6)

0.017

Any diuretic treatment (C03)

972 (73.7)

916 (83.7)

<0.001

 Loop diuretics (C03C)

794 (60.2)

772 (70.6)

<0.001

 Thiazides (C03A, C03B, C03E, C09B C09DA)

357 (27.1)

334 (30.5)

0.061

 Any potassium-saving agent (C03D)

414 (31.4)

420 (38.4)

<0.001

  Aldosterone antagonists (C03DA)

276 (20.9)

264 (24.1)

0.060

All beta blockers (C07)

1,008 (76.4)

845 (77.2)

0.64

 Beta1-selective agents (C07AB, C07F)

873 (66.2)

769 (70.3)

0.031

 Non-selective beta blockers (C07AA)

276 (20.9)

203 (18.6)

0.15

Calcium receptor-blocking agents (C08)

535 (40.6)

452 (41.3)

0.071

RAS-blocking agents (C09)

952 (72.2)

708 (64.7)

<0.001

 ACE inhibitors (C09A, C09B)

776 (58.8)

519 (47.4)

<0.001

 ARB (C09C, C09D)

352 (26.7)

324 (29.6)

0.11

All lipid-lowering drugs (C10A)

670 (50.8)

459 (42.0)

<0.001

 Statins (C10AA)

650 (49.3)

452 (41.3)

<0.001

Number of cardiovascular drugs

  

0.53

0

16 (1.2)

19 (1.7)

 

1

36 (2.7)

18 (1.7)

 

2

69 (5.2)

59 (5.4)

 

3

121 (9.2)

82 (7.5)

 

4

196 (14.9)

158 (14.4)

 

5

264 (20.0)

215 (19.7)

 

6

274 (20.8)

226 (20.7)

 

7

189 (14.3)

182 (16.6)

 

8

107 (8.1)

91 (8.3)

 

9

36 (2.7)

36 (3.3)

 

10

10 (0.8)

8 (0.7)

 

11

1 (0.0)

0 (0.0)

 
  1. Prescription is noted at any time during the time period.