Table 2 Alteration in clinical data of subjects grouped based on percentage change in BDNF 1
| Â | Minor BDNF change | Greater BDNF increase | P |
|---|---|---|---|
(n = 18) | (n = 18) | ||
Body weight (kg) | -7.7±4.8* | -9.1±5.4* |  |
(%) | -8.2%±5.2% | -9.2%±5.2% | 0.752 |
Waist circumference (cm) | -9.3±5.9* | -10.0±5.8* |  |
(%) | -8.5%±5.1% | -9.0%±5.3% | 0.812 |
Systolic BP (mmHg) | -10±18* | -20±22* |  |
(%) | -6.6%±12.9% | -13.6%±13.7% | 0.129 |
Diastolic BP (mmHg) | -5±8* | -10±12* |  |
(%) | -6.4%±9.1% | -11.1%±14.1% | 0.223 |
Fasting glucose (mmol/L) | -0.2±0.5 | -0.4±0.6* |  |
(%) | -2.2%±8.7% | -5.9%±10.9% | 0.159 |
HOMA IR | -1.0±1.0* | -2.3±3.3* |  |
(%) | -24.4%±19.6% | -31.9%±32.1% | 0.229 |
Triglyceride (mmol/L) | -1.5± 3.2* | -0.8±0.9* |  |
(%) | -32.3%±21.5% | -30.9%±28.1% | 0.752 |
Total cholesterol (mmol/L) | -0.6±0.9* | -0.1±0.6* |  |
(%) | -8.3%±13.5% | -3.0%±11.2% | 0.164 |
LDL cholesterol (mmol/L) | -0.4±0.5* | -0.1±0.6 |  |
(%) | -8.5%±18.0% | -2.1%±18.2% | 0.206 |
HDL cholesterol (mmol/L) | 0.1±0.1 | 0.1±0.3 |  |
(%) | 8.8%±15.2% | 8.4%±25.0% | 0.899 |
Serum creatinine | -4.5±8.2* | 1.6±17.7 |  |
(%) | -5.2%±9.2% | 2.2%±18.0% | 0.056 |
AST (U/L) | -7±10* | -11±10* |  |
(%) | -17.0%±25.0% | -28.1%±24.1% | 0.129 |
ALT (U/L) | -12±14* | -19±13* |  |
(%) | -25.6%±27.6% | -36.8%±19.6% | 0.248 |
CRP (mg/L) | -1.7±4.7* | -0.7±2.1 |  |
(%) | -15.9%±78.1% | -1.6%±60.3% | 0.343 |
BDNF (ng/ml) | 0.7±1.9 | 5.7±2.2* |  |
(%) | 3.2%±8.8% | 31.3%±12.4% | <0.001 |
Zung SDS | 2.3±6.7 | -3.9±6.2* |  |
(%) | 8.8%±23.9% | -7.8%±13.9% | 0.009 |