Skip to main content

Table 1 The baseline data of subjects based on percentage change in BDNF 1

From: Brain-derived neurotrophic factor, but not body weight, correlated with a reduction in depression scale scores in men with metabolic syndrome: a prospective weight-reduction study

 

Minor BDNF change

Greater BDNF increase

P

(n = 18)

(n = 18)

Age (year)

41±9

47±11

0.084

Body weight (kg)

95.6±13.8

98.3±11.4

0.319

BMI (kg/m2)

33.5±4.2

33.4±3.6

0.849

Waist circumference (cm)

108.1±10.4

110.0±7.8

0.288

Systolic BP (mmHg)

129±16

141±18

0.059

Diastolic BP (mmHg)

79±12

82±13

0.438

Fasting glucose (mmol/L)

5.5±0.9

5.7±0.7

0.090

Fasting insulin (μIU/ml)

15.6±5.2

22.8±14.0

0.034

HOMA IR

3.9±1.5

5.9±3.7

0.029

Triglyceride (mmol/L)

4.0±7.1

2.5±1.1

0.812

Total cholesterol (mmol/L)

5.5±1.6

5.0±0.7

0.393

LDL cholesterol (mmol/L)

3.3±0.9

3.2±0.6

0.486

HDL cholesterol (mmol/L)

1.0±0.2

1.0±0.2

0.568

Serum creatinine

81.4±12.9

81.2±16.9

0.887

AST (U/L)

28.7±10.4

34.4±11.4

0.081

ALT (U/L)

40±17

48±21

0.241

CRP (mg/L)

3.5±4.8

2.2±2.0

0.558

BDNF (ng/ml)

43.7±7.5

37.2±6.8

0.011

Zung SDS

37.3±7.1

38.0±10.4

0.646

  1. 1cutoff value: median (16.1%) of the change percentage of BDNF.
  2. ALT = alanine aminotransferase, AST = aspartate aminotransferase, BDNF = brain-derived neurotrophic factor, BMI = body mass index, BP = blood pressure, CRP = C-reactive protein, HDL = high-density lipoprotein, HOMA-IR = homeostasis model assessment of insulin resistance, LDL = low-density lipoprotein, Zung SDS = Zung Self-Rating Depression Scale.