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Table 2 Relationships between multiple risk factors and DPN, by univariate and multivariate analysis

From: The relationship between glycemic variability and diabetic peripheral neuropathy in type 2 diabetes with well-controlled HbA1c

Variable Univariate analysis (OR; 95% CI) p Multivariate analysis (OR; 95% CI) p
Age (year) 1.02 (0.96–1.08) 0.497  
Female, n (%) 1.43 (0.62–3.28) 0.400  
Diabetic duration (year) 1.05 (0.97–1.15) 0.224  
Insulin treatment, n (%) 2.13 (0.84–5.36) 0.111  
Lifestyle intervention, n (%) 0.34 (0.11–1.08) 0.067  
Hypertension, n (%) 0.58 (0.25–1.35) 0.205  
Stain medication, n (%) 1.88 (0.69–5.11) 0.216  
Current drinking, n (%) 1.20 (0.52–2.74) 0.673  
Current smoking, n (%) 1.32 (0.57–3.06) 0.521  
BMI (kg/m2) 0.82 (0.72–0.94) 0.005 0.85(0.73–0.99) 0.033
Height (m) 0.97 (0.92–1.03) 0.356  
TG (mmol/L) 0.80 (0.62–1.04) 0.097  
TC (mmol/L) 0.63 (0.42–0.93) 0.020  
HDLC (mmol/L) 0.26 (0.06–1.16) 0.078  
LDLC (mmol/L) 0.40 (0.20–0.80) 0.009  
eGFR (ml/min/1.73 m2) 1.00 (0.98–1.01) 0.478  
Matsuda ISI 1.04 (0.59–1.85) 0.891  
HbA1c (%) 2.45 (0.79–7.64) 0.122  
Hypoglycemia, n (%) 2.15 (0.50–9.21) 0.301  
SDBG (mmol/L) 2.95 (1.55–5.61) 0.001  
MODD (mmol/L) 4.38 (1.48–12.93) 0.008  
MAGE (mmol/L) 2.18 (1.47–3.24) <0.001 2.05 (1.36–3.09) 0.001
  1. Results are given as odds ratios and 95% confidence intervals (OR; 95% CI).
  2. Nagelkerke R2 = 0.317 in multivariate analysis.