| |
DM/–DPN group
|
DM/DPN group
|
t/ χ2
|
p
|
|---|
|
n
|
45
|
45
|
–
|
–
|
|---|
|
Age (year)
|
58.7 ± 6.6
|
59.8 ± 8.3
|
0.675
|
0.501
|
|
Female, n (%)
|
24 (53.3)
|
20 (44.4)
|
0.711
|
0.399
|
|
Diabetic duration (year)
|
5.0 (2.0–8.0)
|
6.0 (2.0–9.0)
|
–
|
0.413
|
|
Insulin treatment, n (%)
|
10 (22.2)
|
17 (37.8)
|
2.593
|
0.107
|
|
Lifestyle intervention, n (%)
|
12 (26.7)
|
5 (11.1)
|
3.554
|
0.059
|
|
Hypertension, n (%)
|
23 (51.1)
|
17 (37.8)
|
1.620
|
0.203
|
|
Stain medication, n (%)
|
8 (17.8)
|
13 (28.9)
|
1.553
|
0.213
|
|
Current drinking, n (%)
|
20 (44.4)
|
22 (48.9)
|
0.179
|
0.673
|
|
Current smoking, n (%)
|
17 (37.8)
|
20 (44.4)
|
0.413
|
0.520
|
|
BMI (kg/m2)
|
26.2 ± 3.9
|
23.9 ± 3.3
|
3.123
|
0.002
|
|
Height (m)
|
1.68 ± 0.07
|
1.66 ± 0.08
|
0.921
|
0.360
|
|
SBP (mmHg)
|
139 ± 18
|
134 ± 18
|
1.317
|
0.191
|
|
DBP (mmHg)
|
83 ± 12
|
80 ± 10
|
1.296
|
0.198
|
|
TG (mmol/L)
|
1.6 (1.0–2.9)
|
1.1 (0.8–1.9)
|
–
|
0.057
|
|
TC (mmol/L)
|
5.0 ± 1.3
|
4.4 ± 1.0
|
2.482
|
0.015
|
|
HDLC (mmol/L)
|
1.2 ± 0.3
|
1.1 ± 0.3
|
1.815
|
0.073
|
|
LDLC (mmol/L)
|
2.7 ± 0.8
|
2.3 ± 0.6
|
2.839
|
0.006
|
|
eGFR (ml/min/1.73 m2)
|
110 ± 26
|
105 ± 22
|
0.706
|
0.482
|
|
Matsuda ISI
|
94(69–145)
|
110 (58–153)
|
–
|
0.707
|
|
HbA1c (%)
|
6.4 ± 0.4
|
6.5 ± 0.4
|
1.576
|
0.119
|
|
Hypoglycemia, n (%)
|
3 (6.7)
|
6 (13.3)
|
1.111
|
0.292
|
|
SDBG (mmol/L)
|
2.1 ± 0.6
|
2.8 ± 0.9
|
3.800
|
<0.001
|
|
MODD (mmol/L)
|
1.9 ± 0.3
|
2.2 ± 0.6
|
2.873
|
0.005
|
|
MAGE (mmol/L)
|
4.5 ± 0.9
|
5.8 ± 1.6
|
2.839
|
<0.001
|
- Normally distributed values in the table are given as the mean ± SD, non-normally distributed values are given as the median (25% and 75% interquartiles), and categorical variables are given as frequency (percentage).
- DM/–DPN group: well-controlled type 2 diabetes without DPN; DM/DPN group: well-controlled type 2 diabetes with DPN.
- BMI: body mass index; SBP/DBP: systolic/diastolic blood pressure; TC: total cholesterol; TG: triglyceride; HDLC: high density lipoprotein cholesterol; LDLC: low density lipoprotein cholesterol; HbA1c: glycosylated hemoglobin A1c; ISI: insulin sensitivity index; eGFR: estimated glomerular filtration rate; SDBG: standard deviation of blood glucose; MODD: mean of daily differences; MAGE: mean amplitude of glycemic excursions.
