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Table 3 Association of irisin with HOMA-β in fully adjusted model

From: Circulating levels of irisin in middle-aged first-degree relatives of type 2 diabetes mellitus — correlation with pancreatic β-cell function

 

NGT

T2DM

 

β

P value

β

P value

Model 1

0.3

0.02

0.053

0.688

Model 2

0.345

0.016

0.006

0.971

Model 3

0.41

0.006

0.056

0.693

Model 4

0.349

0.012

0.069

0.642

Model 5

1.872

0.025

-0.039

0.926

  1. Model 1: unadjusted. Model 2: adjusted for ALT, AST, urea, creatinine, uric acid, and eGFR. Model 3: adjusted for waist circumference, hip circumference, WHR, BMI, muscle mass, fat mass, and percentage body fat. Model 4: adjusted for TC, TG, HDL-C, LDL-C, and FFA. Model 5: adjusted for 2h PG, HbA1C, insulin, and HOMA-IR.
  2. P values < 0.05 were shown in bold.