From: Insulin resistance and associated factors in patients with Type 1 Diabetes
Variables | eGDR 1stquartile | eGDR 2ndand 3rdquartiles | eGDR 4thquartile | P value |
---|---|---|---|---|
Patients | n = 33 (24.4%) | n = 69 (51.1%) | n = 33 (24.4%) | |
Gender (Male) | 18 (54.5%) | 29 (42.0%) | 11 (33.3%) | 0.083 |
Age (years) | 37 (20–68) | 29 (12–58) | 23 (12–55) | < 0.001 |
Duration of diabetes (years) | 21 (2–48) | 14 (1–49) | 10 (0–27) | < 0.001 |
BMI† (kg/m2) | 25 (19–35) | 24 (17–46) | 21 (18–28) | 0.001 |
Waist/height ratio | 52.6 (40.5-70.4) | 50 (38.7-78.8) | 44.2 (36.1-52.2) | < 0.001 |
Total insulin dose IU/Lean mass (kg)§ | 1.13 (0.46-3.15) | 1.14 (0.52-3.35) | 0.91 (0.19-1.63) | 0.059 |
Total lean mass (kg)§ | 40 (32.9-64.2) | 41 (30.1-81.1) | 38.5 (30.1-58.0) | 0.656 |
Thoracoabdominal fat (kg)§ | 9.38 (2.3-28.7) | 6.34 (1.0-20.1) | 4.71 (1.7-12.5) | 0.002 |
Leg fat (kg)§ | 5.40 (0.9-11.0) | 6.29 (0.9-12.9) | 5.89 (1.8-16.3) | 0.901 |
Arm fat (kg)§ | 1.98 (0.3-6.8) | 1.46 (0.2-3.7) | 1.03 (0.3-4.8) | 0.017 |
Total lean mass percentage§ | 0.70 (0.5-0.9) | 0.72 (0.6-1.0) | 0.78 (0.5-0.9) | 0.108 |
Total fat percentage§ | 0.29 (0.07-0.5) | 0.28 (0.05-0.40) | 0.21 (0.08-0.49) | 0.103 |
Thoracoabdominal fat percentage§ | 0.29 (0.09-0.54) | 0.25 (0.05-0.41) | 0.19 (0.08-0.68) | 0.02 |
Leg fat percentage§ | 0.31 (0.06--0.50) | 0.31 (0.06-0.48) | 0.30 (0.11-0.60) | 0.852 |
Arm fat percentage§ | 0.32 (0.55-0.59) | 0.30 (0.4-0.43) | 0.26 (0.45-0.56) | 0.122 |
Triceps skinfold (mm) | 15.5 (6.6-30.0) | 17.8 (4.3-48.7) | 19.0 (5.3-28.7) | 0.730 |
Scapular skinfold (mm) | 19.5 (7.7-39.0) | 17.3 (6.3-41.7) | 13.8 (6.3-26.0) | 0.001 |
Acanthosis (yes)* | 2 (6.5%) | 7 (10.8%) | 1 (3.1%) | 0.432 |
Physical activity (yes) | 17 (53.1%) | 43 (62.3%) | 24 (72.7%) | 0.103 |
Family history of DM2 (yes) | 24 (72.7%) | 43 (66.2%) | 26 (81.3%) | 0.457 |
Total insulin dose (IU/day) | 48 (20–340) | 52.5 (17–161) | 36 (8–85) | 0.041 |
Total Cholesterol (mg/dl) | 166 (104–322) | 166 (85–240) | 165 (76–250) | 0.853 |
HDL (mg/dl) | 56 (27–87) | 52 (32–124) | 58 (32–107) | 0.474 |
LDL (mg/dl) | 100 (57–252) | 96 (20–178) | 93 (35–150) | 0.357 |