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Table 3 Clinical and laboratory characteristics of type 1 diabetic patients compared by eGDR quartiles

From: Insulin resistance and associated factors in patients with Type 1 Diabetes

Variables eGDR 1stquartile eGDR 2ndand 3rdquartiles eGDR 4thquartile P value
Patients n = 33 (24.4%) n = 69 (51.1%) n = 33 (24.4%)  
Gender (Male) 18 (54.5%) 29 (42.0%) 11 (33.3%) 0.083
Age (years) 37 (20–68) 29 (12–58) 23 (12–55) < 0.001
Duration of diabetes (years) 21 (2–48) 14 (1–49) 10 (0–27) < 0.001
BMI (kg/m2) 25 (19–35) 24 (17–46) 21 (18–28) 0.001
Waist/height ratio 52.6 (40.5-70.4) 50 (38.7-78.8) 44.2 (36.1-52.2) < 0.001
Total insulin dose IU/Lean mass (kg)§ 1.13 (0.46-3.15) 1.14 (0.52-3.35) 0.91 (0.19-1.63) 0.059
Total lean mass (kg)§ 40 (32.9-64.2) 41 (30.1-81.1) 38.5 (30.1-58.0) 0.656
Thoracoabdominal fat (kg)§ 9.38 (2.3-28.7) 6.34 (1.0-20.1) 4.71 (1.7-12.5) 0.002
Leg fat (kg)§ 5.40 (0.9-11.0) 6.29 (0.9-12.9) 5.89 (1.8-16.3) 0.901
Arm fat (kg)§ 1.98 (0.3-6.8) 1.46 (0.2-3.7) 1.03 (0.3-4.8) 0.017
Total lean mass percentage§ 0.70 (0.5-0.9) 0.72 (0.6-1.0) 0.78 (0.5-0.9) 0.108
Total fat percentage§ 0.29 (0.07-0.5) 0.28 (0.05-0.40) 0.21 (0.08-0.49) 0.103
Thoracoabdominal fat percentage§ 0.29 (0.09-0.54) 0.25 (0.05-0.41) 0.19 (0.08-0.68) 0.02
Leg fat percentage§ 0.31 (0.06--0.50) 0.31 (0.06-0.48) 0.30 (0.11-0.60) 0.852
Arm fat percentage§ 0.32 (0.55-0.59) 0.30 (0.4-0.43) 0.26 (0.45-0.56) 0.122
Triceps skinfold (mm) 15.5 (6.6-30.0) 17.8 (4.3-48.7) 19.0 (5.3-28.7) 0.730
Scapular skinfold (mm) 19.5 (7.7-39.0) 17.3 (6.3-41.7) 13.8 (6.3-26.0) 0.001
Acanthosis (yes)* 2 (6.5%) 7 (10.8%) 1 (3.1%) 0.432
Physical activity (yes) 17 (53.1%) 43 (62.3%) 24 (72.7%) 0.103
Family history of DM2 (yes) 24 (72.7%) 43 (66.2%) 26 (81.3%) 0.457
Total insulin dose (IU/day) 48 (20–340) 52.5 (17–161) 36 (8–85) 0.041
Total Cholesterol (mg/dl) 166 (104–322) 166 (85–240) 165 (76–250) 0.853
HDL (mg/dl) 56 (27–87) 52 (32–124) 58 (32–107) 0.474
LDL (mg/dl) 100 (57–252) 96 (20–178) 93 (35–150) 0.357
  1. P-value: Jonckheere-Terpstra test, Chi-square for trends, Fisher Exact Test* for comparisons of medians, frequencies and frequencies.
  2. Body mass index = weight (kg)/height (m)2.
  3. §Patients who underwent densitometry for the analysis of body composition (n = 64).