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Table 1 Clinical and laboratory profile of type 1 diabetic patients

From: Insulin resistance and associated factors in patients with Type 1 Diabetes

Variables

Male

Female

P value

N =135

58 (43%)

77 (57%)

 

Age (years)

30 (17–68)

27 (12–58)

0.139

TDM1 duration (years)

15.5 (1–48)

15.0 (1–49)

0.556

eGDR

8.49 (1.26-11.82)

9.3 (2.35-12.6)

0.055

ISS

7.60 (±2.34)

8.30 (±2.28)

0.090

BMI (kg/m2)

24.0 (19.0-36.0)

24.0 (17.0-46.0)

0.255

Waist (cm)

84.5 (65–119)

78.0 (64–123)

0.001

Hips (cm)

98.0 (80–120)

96.0 (90–150)

0.938

Waist/height ratio

49.3(36.1-70.4)

48.1 (38.5-78.9)

0.81

Waist/hip ratio

0.85 (0.75-1.12)

0.79 (0.67-1.48)

<0.001

Total insulin dose UI/Lean mass (kg)

0.98 (0.32-3.15)

1.14 (0.19-3.35)

0.085

Total lean mass (kg)

53.15 (±9.55)

36.82 (41.63)

<0.001

Thoracic-abdominal fat (kg)

3.63 (1.0-28.65)

6.65 (2.34-17.37)

0.053

Leg fat (kg)

3.86 (0.85-12.93)

6.81 (2.3-16.34)

<0.001

Arm fat (kg)

0.738 (0.182-3.743)

1.81 (0.51-6.78)

<0.001

Total lean mass percent

83.8 (56–95)

68.7 (50–86)

<0.001

Total Fat Percent

16.24 (5.3-43.6)

33.00 (14.4-50)

<0.001

Thoracic-abdominal total percent

14.76 (5–68.4)

26.30 (11–50.3)

0.004

Leg fat percent

18.90 (8.7)

39.27 (8.33)

<0.001

Arm fat percent

11.1 (4.1-32.6)

38.0 (14.9-59.1)

<0.001

Triceps skinfold (mm)

12.30 (4.33-31.67)

20.67 (8.33-48.67)

<0.001

Scapular skinfold (mm)

15.70 (6.33-41.67)

18.33 (6.33-39.0)

0.035

Total cholesterol (mg/dL)

160 (76–282)

169 (85–332)

0.043

HDL cholesterol (mg/dL)

50 (27–81)

58 (36–124)

0.001

LDL cholesterol (mg/dL)

94.0 (35–178)

98.0 (20–252)

0.419

Triglycerides (mg/dL)

62.5 (26–310)

63 (25–295)

0.697

Systolic arterial pressure mmHg

120 (90–200)

120 (90–160)

0.012

Diastolic arterial pressure mmHg

80 (50–120)

80 (50–100)

0.017

A1c (%)

7.6 (5.4-11)

7.9 (5.8-11.1)

0.328

HbA1c(mmol/mol)

60 (36–94)

63 (40–98)

0.328

Total insulin dose (IU/kg)

55 (12–340)

44 (8–122)

0.036

Physical activity – yes

41 (70.7%)

43 (56.6%)

0.107

Acanthosis – yes*

4 (7.3%)

6 (8.2%)

0.10

Family history of TDM2 – yes

40 (70.2%)

53 (72.6%)

0.845

  1. P value: Person’s chi- square, Fisher’s exact test*, Student’s T test, and the Mann–Whitney test for differences between, frequencies, frequencies, means and medians.
  2. Body mass index = weight (kg)/height (m)2.
  3. Patients who underwent densitometry for analysis of body composition (n = 64).
  4. eGDR estimated glucose disposal rate, ISS insulin sensitivity score, BMI body mass index, A1c glycated haemoglobin.