Effect of 2 months of ND or HFD on glucose metabolism of rats. Glyceamia (A) and c-peptidemia (B) under fasting and refeeding conditions, glucose tolerance test (IpGTT) (C), and IpGTT area under the curve (D) The data are expressed as the mean ± SEM (ND: n = 6 and HFD: n = 10). *: p < 0.05: significant difference between fasting and refeeding conditions for glycemia or C-peptidemia between ND and HFD rats. ##: p < 0.01: significant difference between ND and HFD C-peptidemia under fasting conditions. $$$ p < 0.001: significant difference between ND and HFD C-peptidemia under refeeding conditions.