| |
T2DM patient’s offspring
|
Control (n = 19) (X + SD)
|
P value
|
|---|
| |
(n = 20) (X + SD)
| |
|---|
|
Age
|
37.15 ± 13.4
|
24.3 ± 3.7
|
<0.005
|
|
BMI
|
29.3 ± 6.0
|
22.8 ± 1.4
|
<0.001
|
|
Waist cm
|
95.3 ± 17.1
|
70.0 ± 7.7
|
<0.0005
|
|
Hip cm
|
106.0 + 17.7
|
95.0 ± 7.7
|
<0.005
|
|
% Fat
|
32.5 ± 11.2
|
25.6 ± 9.8
|
<0.05
|
|
% Lean mass
|
67.5 ± 11.2
|
74.3 ± 9.9
|
<0.05
|
|
Total weight
|
82.54 ± 21.67
|
63.1 ± 9.2
|
<0.0005
|
|
Glucose O
|
90.25 ± 11.47
|
83.9 ± 12.5
|
>0.05
|
|
Glucose 30´
|
140.7 ± 32.76
|
131 ± 30.9
|
>0.05
|
|
Glucose 60´
|
141.2 ± 40.0
|
113.9 ± 25.3
|
<0.05
|
|
Glucose 90´
|
128.5 ± 46.46
|
109.27 ± 33.33
|
>0.05
|
|
Glucose 120
|
120.05 ± 33.21
|
94.9 ± 21.7
|
<0.005
|
|
Insulin 0´
|
11.1 ± 4.9
|
7.3 ± 2.0
|
<0.0005
|
|
Insulin 30´
|
80.7 ± 49.8
|
56.7 ± 24.6
|
<0.05
|
|
Insulin 60´
|
87.7 ± 58.3
|
57.9 ± 36.2
|
<0.05
|
|
Insulin 90´
|
79.4 ± 57.2
|
54.8 ± 35.8
|
<0.05
|
|
Insulin 120´
|
73.2 ± 49.6
|
41.4 ± 37.0
|
<0.0005
|
|
Free fatty acids
|
0.62 ± 0.24
|
0.5 ± 0.3
|
>0.05
|
|
Beta-hydroxybutyrate
|
0.18 ± 0.10
|
0.2 ± 0.3
|
>0.05
|
|
ALP
|
58.5 + 20.17
|
58.6 ± 20.2
|
>0.05
|
|
Uric acid
|
6.21 ± 1.33
|
5.2 ± 1.0
|
<0.05
|
|
Serum creatinine
|
0.91 ± 0.17
|
0.8 + 0.15
|
>0.05
|
|
Cholesterol
|
198.65 ± 28.4
|
200.6 ± 39.6
|
>0.05
|
|
Total bilirubin
|
0.34 ± 0.21
|
0.3 ± 0.2
|
>0.05
|
|
Direct bilirubin
|
0.05 ± 0.04
|
0.06 ± 0.03
|
>0.05
|
|
Indirect bilirubin
|
0.28 ± 0.21
|
0.2 ± 0.18
|
>0.05
|
|
Total protein
|
8.38 ± 0.80
|
8.4 ± 0.9
|
>0.05
|
|
Albumin
|
4.98 ± 0.39
|
5.11 ± 0.5
|
>0.05
|
|
Globulin
|
3.39 ± 0.55
|
3.4 ± 0.5
|
>0.05
|
|
AST
|
14.85 ± 8.64
|
10.4 ± 2.0
|
<0.05
|
|
ALT
|
13.7 ± 8.11
|
8.2 ± 2.6
|
<0.0005
|
|
Triacylglycerol
|
154.2 ± 114.9
|
110.6 ± 71.2
|
>0.05
|
|
C4
|
0.17 ± 0.08
|
0.18 ± 0.08
|
>0.05
|
|
C2
|
9.14 ± 1.44
|
8.7 ± 1.6
|
>0.05
|
|
Leu
|
103.8 ± 21.52
|
96.1 ± 23.7
|
>0.05
|
|
Tyr
|
48.2 ± 10.5
|
41.5 ± 11.0
|
>0.05
|
|
Val
|
138.8 ± 34.2
|
135.0 ± 31.0
|
>0.05
|
|
Gly
|
220.6 ± 38.4
|
226.5 ± 47
|
>0.05
|
|
Arg
|
24.1 ± 7.3
|
27.4 ± 7.84
|
>0.05
|
|
Cit
|
17.9 ± 3.09
|
17.5 ± 4.2
|
>0.05
|
|
Met
|
23.5 ± 6.25
|
22.4 ± 5.2
|
>0.05
|
|
Orn
|
80.2 ± 15.0
|
76.6 ± 9.5
|
>0.05
|
|
Phe
|
41.1 ± 8.3
|
39.3 ± 10.8
|
>0.05
|
|
Ala
|
231.0 ± 45.23
|
238.0 ± 44.2
|
>0.05
|
- NOTE: Parameters in bold were significant.
