Risk factor1 | Overall effect size | Effect size change for intervention attributes and other factors | Residual heterogeneity | ||||
---|---|---|---|---|---|---|---|
Estimate ± SE | P- value | Explanatory Variables2 | Estimate ± SE3 | P-value | τ2 | P-value | |
FI (mU/L) | -2.56 ± 0.58 | <0.001 | Presence of IGT, IR or MetS | -1.20 ± 0.69 | 0.082 | 1.523 ± 0.773 | <0.001 |
 |  |  | Calorie restriction (100 kcal/d) | -0.68 ± 0.26 | 0.009 |  |  |
 |  |  | Incorporation of resistance training | 1.72 ± 0.81 | 0.034 |  |  |
FG (mmol/L) | -0.18 ± 0.04 | <0.001 | Presence of IGT, IR or MetS | -0.08 ± 0.05 | 0.098 | 0.010 ± 0.004 | <0.001 |
 |  |  | After a follow-up period | 0.13 ± 0.06 | 0.034 |  |  |
SBP (mm Hg) | -2.77 ± 0.56 | <0.001 | Presence of IGT, IR or MetS | -3.23 ± 1.00 | 0.001 | 2.796 ± 1.419 | <0.001 |
 |  |  | Calorie restriction (100 kcal/d) | -0.64 ± 0.23 | 0.006 |  |  |
 |  |  | Length of intervention (months) | 0.13 ± 0.03 | <0.001 |  |  |
HDL (mmol/L) | -0.015 ± 0.015 | 0.305 | Age at baseline (years) | -0.006 ± 0.002 | 0.021 | 0.005 ± 0.002 | <0.001 |
 |  |  | Fraction of women participants | -0.086 ± 0.046 | 0.065 |  |  |
TAG (mmol/L) | -0.258 ± 0.037 | <0.001 | Calorie restriction (100 kcal/d) | -0.061 ± 0.017 | <0.001 | 0.029 ± 0.009 | <0.001 |
 |  |  | Baseline TAG (mmol/L) | -0.243 ± 0.076 | 0.001 |  |  |
BMI (kg/m2) | -1.61 ± 0.13 | <0.001 | Calorie restriction (100 kcal/d) | -0.22 ± 0.08 | 0.003 | 0.353 ± 0.125 | <0.001 |
 |  |  | Fat intake restriction (% Energy) | -0.10 ± 0.03 | 0.003 |  |  |
 |  |  | Exercise session duration (10 min) | -0.24 ± 0.12 | 0.055 |  |  |
 |  |  | Baseline BMI (kg/m2) | -0.07 ± 0.04 | 0.095 |  |  |