Table 4 Results of melatonin versus placebo on clinic blood pressure, stratified by African-American or white race
From: Melatonin supplementation to treat the metabolic syndrome: a randomized controlled trial
Parameter | Melatonin | Placebo | P value (mixed model) |
|---|---|---|---|
SBP average clinic value, mmHg (mean, SD) | (n = 39, 38) | (n = 38, 37) |  |
  Whites (n = 22) |  |  |  |
  Pre | 123.2 ± 12.7 | 121.4 ± 11.4 |  |
  Post | 119.4 ± 10.9 | 122.9 ± 12.4 |  |
  Change with treatment (post minus pre) | -2.6 ± 11.0 | 1.7 ± 12.0 | 0.196 |
  African-Americans (n = 13) |  |  |  |
  Pre | 131.0 ± 21.0 | 119.1 ± 22.1 |  |
  Post | 127.1 ± 18.4 | 131.6 ± 18.0 |  |
  Change with treatment (post minus pre) | -3.9 ± 10.9 | 12.5 ± 13.7 | 0.003 |
DBP average clinic value, mmHg (mean, SD) | (n = 39, 38) | (n = 38, 37) |  |
  Whites (n = 22) |  |  |  |
  Pre | 73.3 ± 8.4 | 73.1 ± 5.9 |  |
  Post | 71.1 ± 5.6 | 72.9 ± 6.3 |  |
  Change with treatment (post minus pre) | -1.3 ± 7.2 | 0.0 ± 5.0 | 0.840 |
  African-Americans (n = 13) |  |  |  |
  Pre | 80.7 ± 14.2 | 76.2 ± 13.7 |  |
  Post | 79.3 ± 14.4 | 81.1 ± 13.3 |  |
  Change with treatment (post minus pre) | -1.4 ± 6.6 | 4.9 ± 8.6 | 0.034 |