Supplementary use of HbA1c as hyperglycemic criterion to detect metabolic syndrome

Table 1 Basal characteristics of the subjects

	All n = 229	MetS-positive n = 109	MetS-negative n = 120	P-value
Age (years)	58.7 ± 10.5	59.1 ± 10.6	58.3 ± 10.4	0.556
WC (cm)	85.9 ± 10.6	92.8 ± 8.2	79.6 ± 8.3	<0.001
SBP (mmHg)	139.5 ± 20.3	145.3 ± 17.7	134.1 ± 21.1	<0.001
DBP (mmHg)	79.4 ± 11.1	82.5 ± 10.9	76.7 ± 10.6	<0.001
FPG (mmol/L)	5.3 ± 0.6	5.6 ± 0.6	5.0 ± 0.4	<0.001
TG (mmol/L)	1.5 ± 0.7	1.9 ± 0.7	1.2 ± 0.5	<0.001
HDL (mmol/L)	1.4 ± 0.3	1.2 ± 0.3	1.6 ± 0.3	<0.001
HbA1c (%)	6.1 ± 0.5	6.3 ± 0.6	5.9 ± 0.4	<0.001
Correlation coefficient between HbA1c and FPG	0.593, P < 0.001	0.569, P < 0.001	0.397, P < 0.001

Note: SBP, systolic blood pressure; DBP, diastolic blood pressure; WC, waist circumference; HDL, high-density lipoprotein cholesterol; TG, triglyceride; FPG, fasting plasma glucose; HbA1c, haemoglobin A1c; data are expressed as mean ± standard deviation. Metabolic syndrome (MetS) was diagnosed according to the guideline of the United States National Cholesterol Education Program (NCEP) Expert Panel Adult Treatment Panel (ATP) III criteria, in which an individual diagnosed with MetS has three or more of following characteristics: 1) central obesity (waist circumference exceeds 90 cm or 80 cm for Asian male and female, respectively), 2) hypertension (systolic pressure equals or exceed 130 mmHg or diastolic pressure equals or exceeds 85 mmHg), 3) elevated blood glucose (fasting glucose level equals or exceeds 5.6 mmol/L [100 mg/dL]), 4) elevated plasma triglycerides (level equals or exceeds 1.70 mmol/L [150 mg/dL]), and 5) low level of high-density lipoprotein-cholesterol (HDL-C; level equals or is less than 40 mg/dL for male and 50 mg/dL for female)[19].

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