Table 3 Odds ratios and 95% confidence intervals for BMI and metabolic syndrome single features by breast cancer subtypes
From: Metabolic syndrome-breast cancer link varies by intrinsic molecular subtype
Risk factor | Luminal A breast cancer (n = 191) | Luminal B breast cancer (n = 119 ) | HER-2+ breast cancer (n = 27) | Triple Negative breast cancer (n = 46) | ||||
|---|---|---|---|---|---|---|---|---|
OR (CI 95%) | p | OR (CI 95%) | p | OR (CI 95%) | p | OR (CI 95%) | p | |
BMI ≥ 25 Kg/m 2 | 1.12 (0.96-2.39) | 0.2 | 0.97 (0.46-1.99) | 0.9 | 0.54 (0.23-1.28) | 0.1 | 0.50 (0.16-1.45) | 0.2 |
WC ≥ 88 cm | 1.12 (0.65-1.91) | 0.6 | 2.21 ( 0.77-2.60) | 0.1 | 2.72 (1.69-10.72) | 0.01 | 0.91 (0.66-1.25) | 0.1 |
WHR ≥ 0.8 | 0.9 (0.45-1.73) | 0.7 | 0.92 (0.45-1.87) | 0.8 | 1.89 (1.6-4.1) | 0.8 | 0.61 (0.21-1.74) | 0.4 |
HOMA-IR | 0.68 (0.39-1-19) | 0.1 | 2.33 (1.2-4.2) | 0.006 | 2.11 (1.66-6.59) | 0.05 | 1 (0.7-1.4) | 0.1 |
Serum fasting glucose | 1.21 (0.70-2.08) | 0.1 | 1.5 (0.9-2.1) | 0.6 | 1.34 (0.34-5.3) | 0.6 | 0.59 ( 0.17-1.9) | 0.3 |
Hyperinsulinemia | 0.99 (0.44-2.19) | 0.9 | 0.51 (0.21-1.24) | 0.1 | 0.44 (0.05-3.92) | 0.4 | 0.21 (0.0700.65) | 0.7 |
Hypertension | 0.51 (0.30-0.88) | 0.1 | 1.35 (0.76-2.41) | 0.3 | 3.27 (0.95-11.26) | 0.06 | 0.69 (0.28-1.70) | 0.4 |
Triglycerides | 0.64 (0.32-1.29) | 0.2 | 1.31 (0.62-2.78) | 0.4 | 1.48 (0.29-7.41) | 0.6 | 0.74 (0.22-2.44) | 0.6 |
HDL-Cholesterol | 1.12 (0.65-1.91) | 0.6 | 1.15 (0.65-2.05) | 0.6 | 1.08 (0.59-1.95) | 0.5 | 1.5 (0.67-3.46) | 0.3 |