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Table 3 Odds ratios and 95% confidence intervals for BMI and metabolic syndrome single features by breast cancer subtypes

From: Metabolic syndrome-breast cancer link varies by intrinsic molecular subtype

Risk factor Luminal A breast cancer (n = 191) Luminal B breast cancer (n = 119 ) HER-2+ breast cancer (n = 27) Triple Negative breast cancer (n = 46)
  OR (CI 95%) p OR (CI 95%) p OR (CI 95%) p OR (CI 95%) p
BMI ≥ 25 Kg/m 2 1.12 (0.96-2.39) 0.2 0.97 (0.46-1.99) 0.9 0.54 (0.23-1.28) 0.1 0.50 (0.16-1.45) 0.2
WC ≥ 88 cm 1.12 (0.65-1.91) 0.6 2.21 ( 0.77-2.60) 0.1 2.72 (1.69-10.72) 0.01 0.91 (0.66-1.25) 0.1
WHR ≥ 0.8 0.9 (0.45-1.73) 0.7 0.92 (0.45-1.87) 0.8 1.89 (1.6-4.1) 0.8 0.61 (0.21-1.74) 0.4
HOMA-IR 0.68 (0.39-1-19) 0.1 2.33 (1.2-4.2) 0.006 2.11 (1.66-6.59) 0.05 1 (0.7-1.4) 0.1
Serum fasting glucose 1.21 (0.70-2.08) 0.1 1.5 (0.9-2.1) 0.6 1.34 (0.34-5.3) 0.6 0.59 ( 0.17-1.9) 0.3
Hyperinsulinemia 0.99 (0.44-2.19) 0.9 0.51 (0.21-1.24) 0.1 0.44 (0.05-3.92) 0.4 0.21 (0.0700.65) 0.7
Hypertension 0.51 (0.30-0.88) 0.1 1.35 (0.76-2.41) 0.3 3.27 (0.95-11.26) 0.06 0.69 (0.28-1.70) 0.4
Triglycerides 0.64 (0.32-1.29) 0.2 1.31 (0.62-2.78) 0.4 1.48 (0.29-7.41) 0.6 0.74 (0.22-2.44) 0.6
HDL-Cholesterol 1.12 (0.65-1.91) 0.6 1.15 (0.65-2.05) 0.6 1.08 (0.59-1.95) 0.5 1.5 (0.67-3.46) 0.3