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Table 1 Metabolic parameters of SD rats in different groups

From: Atorvastatin inhibits the expression of RAGE induced by advanced glycation end products on aortas in healthy Sprague–Dawley rats

  Body weight Serum glucose LDL-c
  12th week 24th week 12th week 24th week 12th week 24th week
Group A 603.40 ± 37.72 750.20 ± 40.24 5.62 ± 0.28 6.29 ± 0.24 2.78 ± 0.62 1.81 ± 0.38
Group B 621.25 ± 46.82 720.36 ± 33.69 6.18 ± 0.67 5.79 ± 0.66 1.74 ± 0.58 1.79 ± 0.52
Group C 630.13 ± 28.41 784.35 ± 38.53 5.98 ± 1.16 5.72 ± 0.69 2.08 ± 0.37 2.24 ± 0.42
Group D 626.38 ± 32.32 806.61 ± 48.25* 5.95 ± 0.92 6.24 ± 0.75 2.04 ± 1.01 2.08 ± 0.85
Group E 616.13 ± 42.38 771.5 ± 40.08 5.62 ± 0.90 6.20 ± 0.28 2.74 ± 0.29 2.72 ± 0.36
  1. Group A: absolute controls, (n = 10); Group B: high fat diet (n = 10); Group C: high fat diet plus AGEs with glycated-BSA 20 mg/kg body weight (n = 10); Group D: high fat diet plus AGEs with glycated-BSA 40 mg/kg (n = 10)#Group E: high fat diet plus AGEs with glycated-BSA 40 mg/kg and atorvastatin. Each value represents the mean ± S.D. * = p < 0.05 vs. other groups at the end of 24th week.