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Table 1 Metabolic parameters of SD rats in different groups

From: Atorvastatin inhibits the expression of RAGE induced by advanced glycation end products on aortas in healthy Sprague–Dawley rats

 

Body weight

Serum glucose

LDL-c

 

12th week

24th week

12th week

24th week

12th week

24th week

Group A

603.40 ± 37.72

750.20 ± 40.24

5.62 ± 0.28

6.29 ± 0.24

2.78 ± 0.62

1.81 ± 0.38

Group B

621.25 ± 46.82

720.36 ± 33.69

6.18 ± 0.67

5.79 ± 0.66

1.74 ± 0.58

1.79 ± 0.52

Group C

630.13 ± 28.41

784.35 ± 38.53

5.98 ± 1.16

5.72 ± 0.69

2.08 ± 0.37

2.24 ± 0.42

Group D

626.38 ± 32.32

806.61 ± 48.25*

5.95 ± 0.92

6.24 ± 0.75

2.04 ± 1.01

2.08 ± 0.85

Group E

616.13 ± 42.38

771.5 ± 40.08

5.62 ± 0.90

6.20 ± 0.28

2.74 ± 0.29

2.72 ± 0.36

  1. Group A: absolute controls, (n = 10); Group B: high fat diet (n = 10); Group C: high fat diet plus AGEs with glycated-BSA 20 mg/kg body weight (n = 10); Group D: high fat diet plus AGEs with glycated-BSA 40 mg/kg (n = 10)#Group E: high fat diet plus AGEs with glycated-BSA 40 mg/kg and atorvastatin. Each value represents the mean ± S.D. * = p < 0.05 vs. other groups at the end of 24th week.