Immunohistochemical staining of AGEs in aortic wall. A1-E1, Group A-Group E at the end of the 12th week; A2-E2, Group A-Group E at the end of the 24th week. The presence of antigen is indicated by a red-brownish color which was labeled by arrows. Immunoreactivity was positive in the intima. Original magnification is × 200 for all photographs. L: lumen; I: intima; A: adventitia.