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Figure 5 | Diabetology & Metabolic Syndrome

Figure 5

From: Pioglitazone modulates the proliferation and apoptosis of vascular smooth muscle cells via peroxisome proliferators-activated receptor-gamma

Figure 5

Pioglitazone regulated activities of caspases. A. The activity of the effector caspase3/7 was shown in the control, GW9662, Pioglitazone, PIO + siRNA-PPARγ and PIO + wt-PPARγ treated VSMCs, respectively. B. The activity of the initial caspase of intrinsic pathway-caspase8 in different gr006Fups. C. The activity of the initial caspase of extrinsic pathway-caspase9 in different groups. **P < 0.001, ***P < 0.0001. The activity of different caspases is normalized to the control (100%). Percentage is presented as the mean ± SEM of triplicates. Each experiment has been repeated three times.

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