Skip to main content

Advertisement

Table 1 Follow-up of body weights and glucose concentrations

From: Caloric restriction or telmisartan control dyslipidemia and nephropathy in obese diabetic Zücker rats

  Body weight (g)   Glucose (mg/dL)  
Animal 10 19 Weight increase 10 19 Glucose increase
Z 330 ± 23 517 ± 34 187 ± 35 150 ± 16 188 ± 78 38 ± 72
ZDFV 356 ± 22 433 ± 35* 76 ± 22* 201 ± 96 593 ± 63* 416 ± 103*
ZDFT 360 ± 14 480 ± 68 119 ± 62 223 ± 130 478 ± 115 218 ± 121
ZDFD 337 ± 13 495 ± 15 158 ± 14 146 ± 23 360 ± 119 213 ± 130
  1. Differences between the experimental time-points (weeks 10 and 19) in the non-diabetic and diabetic obese rats. Data are shown as mean ± SD. Significant differences *p < 0.05 vs Zücker, p < 0.05 vs ZDFV. The greater weight increase was seen in the non-diabetic rats (Z) and the fatty-diabetic animals subjected to caloric restriction (ZDFD). Conversely, in the vehicle group (ZDFV), we saw a trend to a slower weight gain but the most marked increase in hyperglycaemia over time.