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Table 2 Metabolic characteristics of the cohort categorized according to the use of Diuretics 1

From: Impact of chronic diuretic treatment on glucose homeostasis

 

Use of Diuretics

 
 

No

Yes

P2

 

(n = 890)

(n = 71)

 

Body weight (kg)

72.9 ± 15.5

82.8 ± 17.9

< 0.001

BMI (kg/m2)

27.5 ± 5.2

31.5 ± 6.2

< 0.001

Circumference:

   

   Waist (cm)

93.6 ± 13.8

102.4 ± 18.3

< 0.001

   Hip (cm)

104.1 ± 11.7

110.0 ± 16.8

< 0.001

Systolic BP (mmHg)

129.1 ± 16.2

134.9 ± 17.7

0.005

Diastolic BP (mmHg)

78.6 ± 9.8

79.6 ± 9.6

0.22

Heart rate (beats/min)

74.3 ± 11.3

72.5 ± 11.6

0.18

Random capillary blood glucose (mg/dl)

87 ± 20

95 ± 23

0.001

Blood concentration of

n = 468

n = 39

 

   Glycated hemoglobin (%)

5.6 ± 0.43

5.8 ± 0.47

< 0.001

   (mmol/mol)

37.2 ± 4.7

40.2 ± 5.2

 

   Glucose (mg/dL)

90 ± 11

99 ± 13

< 0.001

   Total cholesterol (mg/dL)

213 ± 39

211 ± 43

0.69

   HDL cholesterol (mg/dL)

60 ± 15

57 ± 12

0.52

   Triglycerides (mg/dL)

100 ± 50

111 ± 35

0.008

   LDL cholesterol (mg/dL)

134 ± 36

132 ± 38

0.71

   Uric acid (mg/dL)

4.9 ± 1.4

5.8 ± 1.7

< 0.001

   Insulin (μU/mL)

9.2 ± 5.5

13.2 ± 8.3

< 0.001

HOMA-I

2.10 ± 1.41

3.31 ± 2.43

< 0.001

   Creatinine (mg/dL)

0.83 ± 0.21

0.87 ± 0.30

0.93

GFR - MDRD (mL/min/1.73 m2)

92.4 ± 19.1

90.8 ± 23.9

0.89

  1. 1 All data are reported as means ± SD.
  2. 2 Unpaired Student’s t-test.
  3. BMI: body mass index; BP: blood pressure; GFR: glomerular filtration rate; HDL: high-density lipoproteins; HOMA-I: homeostasis model assessment of insulin resistance; LDL: low-density lipoproteins; MDRD: Modification of Diet in Renal Disease Study.
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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