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Table 2 Metabolic characteristics of the cohort categorized according to the use of Diuretics 1

From: Impact of chronic diuretic treatment on glucose homeostasis

  Use of Diuretics  
  No Yes P2
  (n = 890) (n = 71)  
Body weight (kg) 72.9 ± 15.5 82.8 ± 17.9 < 0.001
BMI (kg/m2) 27.5 ± 5.2 31.5 ± 6.2 < 0.001
Circumference:    
   Waist (cm) 93.6 ± 13.8 102.4 ± 18.3 < 0.001
   Hip (cm) 104.1 ± 11.7 110.0 ± 16.8 < 0.001
Systolic BP (mmHg) 129.1 ± 16.2 134.9 ± 17.7 0.005
Diastolic BP (mmHg) 78.6 ± 9.8 79.6 ± 9.6 0.22
Heart rate (beats/min) 74.3 ± 11.3 72.5 ± 11.6 0.18
Random capillary blood glucose (mg/dl) 87 ± 20 95 ± 23 0.001
Blood concentration of n = 468 n = 39  
   Glycated hemoglobin (%) 5.6 ± 0.43 5.8 ± 0.47 < 0.001
   (mmol/mol) 37.2 ± 4.7 40.2 ± 5.2  
   Glucose (mg/dL) 90 ± 11 99 ± 13 < 0.001
   Total cholesterol (mg/dL) 213 ± 39 211 ± 43 0.69
   HDL cholesterol (mg/dL) 60 ± 15 57 ± 12 0.52
   Triglycerides (mg/dL) 100 ± 50 111 ± 35 0.008
   LDL cholesterol (mg/dL) 134 ± 36 132 ± 38 0.71
   Uric acid (mg/dL) 4.9 ± 1.4 5.8 ± 1.7 < 0.001
   Insulin (μU/mL) 9.2 ± 5.5 13.2 ± 8.3 < 0.001
HOMA-I 2.10 ± 1.41 3.31 ± 2.43 < 0.001
   Creatinine (mg/dL) 0.83 ± 0.21 0.87 ± 0.30 0.93
GFR - MDRD (mL/min/1.73 m2) 92.4 ± 19.1 90.8 ± 23.9 0.89
  1. 1 All data are reported as means ± SD.
  2. 2 Unpaired Student’s t-test.
  3. BMI: body mass index; BP: blood pressure; GFR: glomerular filtration rate; HDL: high-density lipoproteins; HOMA-I: homeostasis model assessment of insulin resistance; LDL: low-density lipoproteins; MDRD: Modification of Diet in Renal Disease Study.