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Table 2 Risk of Metabolic syndrome and its components may modify by circulating PPARγ in the obese subjects

From: Crosstalk between circulating peroxisome proliferator-activated receptor gamma, adipokines and metabolic syndrome in obese subjects

Metabolic syndrome and its components Odd ratio 95% CI P
Metabolic syndrome‡    
Model 1 1.85 1.07-3.20 0.02
Model 2¶ 2.05 1.14-3.67 0.01
Model 3† 1.90 1.04-3.47 0.03
Model 4§ 1.88 1.01-3.49 0.04
Abdominal Obesity (WC)    
Model 1 3.889 1.49-10.14 0.005
Model 2 5.069 1.66-15.43 0.004
Model 3 4.820 1.30-17.75 0.018
Model 4 5.199 1.07-25.26 0.04
Hyperglycemia*    
Model 1 1.47 0.77-2.79 0.23
Model 2 1.55 0.80-2.99 0.18
Model 3 1.42 0.71-2.81 0.31
Model 4 1.39 0.67-2.88 0.37
Hypertension    
Model 1 1.22 0.71-2.10 0.46
Model 2 1.49 0.71-3.14 0.28
Model 3 1.33 0.62-2.87 0.46
Model 4 1.15 0.51-2.61 0.72
Low HDL    
Model 1 1.70 0.96-3.02 0.06
Model 2 1.71 0.95-3.06 0.07
Model 3 1.63 0.90-2.95 0.10
Model 4 1.62 0.89-2.95 0.11
Hypertriglyceridemia    
Model 1 1.636 0.933-2.869 0.086
Model 2 1.706 0.957-3.042 0.070
Model 3 1.593 0.884-2.870 0.121
Model 4 1.545 0.84-2.83 0.16
  1. Logistic regression model for circulating PPARγ effect on Risk of Metabolic syndrome and its components.
  2. Total n = 96, n of men =18, n of women = 78, mean of age = 39.06, mean of BMI = 35.34.
  3. The significant value presented by bold format.
  4. ‡The MetS was defined based on the National Cholesterol Education Program Adult Treatment Panel III criteria as presenting at least three of the following components: 1) waist circumferences 102 cm or greater in men or 88 cm or greater in women; 2) triglycerides 1.7 mmol/liter (150 mg/dl) or greater; 3) HDL cholesterol less than 1.03 mmol/liter (40 mg/dl) in men or less than 1.29 mmol/liter (50 mg/dl) in women; 4) blood pressure 130/85 mm Hg or greater or current use of antihypertensive medications; or 5) fasting plasma glucose 6.1 mmol/liter (110 mg/dl) or greater.
  5. Step 1 in Logistic regression model; MetS entered as dependent and categorized PPARγ (low and high concentration of PPARγ based on median) entered as covariates as a first model.
  6. ¶Age, gender entered on Step 1.
  7. †Body Mass Index entered on Step 2.
  8. § Body composition components including fat mass and FFM entered on Step 3.
  9. MetS, metabolic syndrome; WC, waist circumferences; HDL, high density lipoprotein.