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Table 1 Clinical characteristics of subjects

From: The association and predictive value analysis of metabolic syndrome combined with resting heart rate on cardiovascular autonomic neuropathy in the general Chinese population

Variable

Entire sample

Subjects without CAN

Subjects with CAN

P value*

Demographic information

    

 N

2096

1705

387

 

 Age (years)

60.42 ± 8.68

59.85 ± 8.64

62.94 ± 8.43

<0.001

 Gender (male,%)

705(33.7%)

562(32.96%)

143(36.95%)

0.134

 BMI (kg/m2)

24.21 ± 3.37

24.07 ± 3.28

24.84 ± 3.7

<0.001

 WC (cm)

85.07 ± 9.77

84.47 ± 9.62

87.72 ± 9.99

<0.001

 SBP (mmHg)

127.62 ± 18.77

126.39 ± 18.22

133.05 ± 20.19

<0.001

 DBP (mmHg)

79.83 ± 9.74

79.5 ± 9.65

81.31 ± 10.01

0.001

Laboratory measurement

    

 FPG (mmol/L)

5.53 ± 1.82

5.4 ± 1.58

6.12 ± 2.54

<0.001

 PBG (mmol/L)

7.67 ± 3.63

7.36 ± 3.3

9.07 ± 4.6

<0.001

 HbAlc (%)

6 ± 1.08

5.89 ± 0.92

6.47 ± 1.54

<0.001

 FINS uml

7.19 ± 11.86

6.74 ± 8.03

9.18 ± 21.71

<0.001

 IR (mmol/L)

1.81 ± 3.31

1.64 ± 2.13

2.54 ± 6.22

<0.001

 TC (mmol/L)

5.32 ± 1

5.31 ± 0.98

5.39 ± 1.05

0.142

 TG (mmol/L)

1.71 ± 0.98

1.67 ± 0.93

1.9 ± 1.17

<0.001

 HDL (mmol/L)

1.36 ± 0.32

1.36 ± 0.33

1.34 ± 0.32

0.203

 LDL (mmol/L)

3.19 ± 0.77

3.18 ± 0.76

3.23 ± 0.81

0.229

 SCr (μmol/L)

77.81 ± 26.11

77.65 ± 26.96

78.51 ± 21.98

0.561

 UA (μmol/L)

281.21 ± 84.01

280.13 ± 83.47

285.99 ± 86.26

0.216

HRV indices

    

 HR (bpm)

72.42 ± 10.13

70.77 ± 9.08

79.7 ± 11.26

<0.001

 TP (ms2)

873.95 ± 702.47

1000.63 ± 693.2

315.87 ± 410.75

<0.001

 LF (ms2)

190.98 ± 207.88

224.34 ± 215.08

43.97 ± 57.29

<0.001

 HF (ms2)

183.05 ± 219.43

215.11 ± 229.61

41.82 ± 59.63

<0.001

 LF/HF

1.7 ± 1.98

1.55 ± 1.48

2.37 ± 3.32

<0.001

Medical history

    

 Smoking (yes,%)

306(14.63%)

244(14.31%)

62(16.02%)

0.39

 MetS (yes,%)

833(39.82%)

629(36.89%)

204(52.71%)

<0.001

 DM (yes,%)

446(21.33%)

307(18.02%)

139(35.92%)

<0.001

 HT (yes,%)

976(46.65%)

735(43.11%)

241(62.27%)

<0.001

  1. Note: *present the difference between subjects with and without cardiovascular autonomic neuropathy (CAN). BMI- Body mass index, WC-waist circumference, SBP- systolic blood pressure, DBP- diastolic blood pressure, FPG- fasting plasma glucose, PBG- plasma blood glucose, FINS- fasting blood insulin, IR-insulin resistance, TC- serum total cholesterol, TG- triglyceride, UA- uric acid, HDL- high-density lipoprotein cholesterol, LDL- low density lipoprotein cholesterol, SCr- serum creatinine, HR-heart rate, TP-total power of variance, LF-low frequency, HF-high frequency, MetS- metabolic syndrome, HT- Hypertension, DM- Diabetes.