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Table 1 Morphological and functional characteristics of salivary glands of Wistar Kyoto (WKY) rats, diabetic WKY (WKY-D), spontaneously hypertensive rats (SHR) and diabetic SHR (SHR-D)

From: Increased SGLT1 expression in salivary gland ductal cells correlates with hyposalivation in diabetic and hypertensive rats

  WKY WKY-D SHR SHR-D
Parotid weight (mg) 156 ± 5.6 101 ± 6.1*** 138 ± 4.6# 124 ± 4.2##
Submandibular weight (mg) 288 ± 7.8 245 ± 13.8* 286 ± 7.2 234 ± 8.4**
Absolute salivary secretion (μL/7 min) 14.4 ± 0.6 6.7 ± 0.40*** 8.0 ± 0.81### 3.5 ± 0.18***###
Relative salivary secretion (μl/g tissue/min) 4.6 ± 0.05 2.7 ± 0.06*** 2.7 ± 0.07### 1.4 ± 0.02***###
Basal salivary glucose (mg/dL) 6.5 ± 0.32 23.4 ± 1.7*** 3.2 ± 0.30# 16.4 ± 1.3***###
  1. Relative salivary secretion was calculated taking into account the sum of parotid and submandibular weights. Data are means ± S.E.M of 5 animals. *P < 0.05, **P < 0.01 and ***P < 0.001 vs respective non-diabetic group; #P < 0.05, ##P < 0.01, ###P < 0.001 vs respective normotensive (WKY) group; One-Way ANOVA, Student-Newman-Keuls post-test.