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Table 1 Effectiveness of metformin in diabetes prevention of patients with impaired glucose tolerance

From: Metformin: an old but still the best treatment for type 2 diabetes

Study Randomized Country N Duration years Mean change in risk MET (%) Mean change in risk LSM (%)
DPP [7] yes USA 3234 3 −31% −58%
IDPP [9] yes India 522 3 −26.4% −28.2%
Yang et al.[10] yes China 321 2.5 −77% -
DPPOS [11] yes USA 2766 5.7 −18% −34%
  1. DPP: Diabetes Prevention Program, DPP: Indian Diabetes Prevention Program, DPPOS: Diabetes Prevention Outcome Study, MET: Metformin, LSM: Lifestyle modification.